3-(Trifluoromethyl)-1,2,4-oxadiazol-5-amine CAS 35488-61-0
| CAS No. | 35488-61-0 |
| Molecular Formula | C3H2F3N3O |
| Molecular Weight | 153.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 3-(Trifluoromethyl)-1,2,4-oxadiazol-5-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
3-(Trifluoromethyl)-1,2,4-oxadiazol-5-amine (CAS 35488-61-0), molecular formula C3H2F3N3O and molecular weight 153.06 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-(Trifluoromethyl)-1,2,4-oxadiazol-5-amine (C3H2F3N3O) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C3H2F3N3O |
| Molecular Weight | 153.06 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1967 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Trifluoromethyl Standards
- 3-(Trifluoromethyl)isoxazol-5-ol (CAS 110411-51-3)
- 5-(Trifluoromethyl)-1,2,4-oxadiazol-3-amine (CAS 883877-86-9)
- 5-(Trifluoromethyl)isoxazol-3(2H)-one (CAS 388091-41-6)
- (5S)-5-(trifluoromethyl)pyrrolidin-2-one (CAS 1287211-10-2)
- (R)-5-(Trifluoromethyl)pyrrolidin-2-one (CAS 1311255-07-8)
- 5-(Trifluoromethyl)pyrrolidin-2-one (CAS 141519-28-0)
- (4R)-4-(trifluoromethyl)pyrrolidin-2-one (CAS 1431299-15-8)
- 1-(trifluoromethyl)cyclopropane-1-carboxamide (CAS 1628184-67-7)
Recommended Standards
- 1-Bromopentane-1,1-d2 (CAS 77734-75-9)
- 1-Bromo-2,2-dimethylpropane-d (CAS 38581-03-2)
- Trifluoroethanecarbonyl isocyanate (CAS 14565-32-3)
- (E)-(3-(Hydroxyamino)prop-1-en-1-yl)phosphonic acid (CAS 66508-29-0)
- 6-Benzyl-3-bromo-5,6,7,8-tetrahydro-1,6-naphthyridine (CAS 1000576-67-9)
- 3-Methyl-3-(2-methyl-2,3-dihydrobenzofuran-5-yl)butan-1-amine (CAS 1516068-12-4)
- 4-(Difluoromethyl)-6-iodo-3-methyl-2-(trifluoromethyl)pyridine (CAS 1804867-49-9)
- trans-(4-hydroxycyclohexyl) benzoate (CAS 917771-54-1)
- [2,2'-Bipyridine]-5,5'-diyldimethanamine (CAS 303050-46-6)
- (2R,3S,4S,5R,6S)-2-(acetoxymethyl)-6-methoxytetrahydro-2H-pyran-3,4,5-triyl triacetate (CAS 5019-22-7)
- Lisinopril Impurity 11 (CAS CATO-C4X-168111)
- Ethyl 2-((8-chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl)thio)-2,2-difluoroacetate (CAS 1823182-39-3)
- 1,5-Dichloro-2-iodo-3-methylbenzene (CAS 175277-97-1)
- Semaglutide impurity 80 (CAS CATO-C4X-222680)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com