Methyl 2-amino-3-(5-bromo-1h-indol-3-yl)propanoate CAS 355017-52-6
| CAS No. | 355017-52-6 |
| Molecular Formula | C12H13BrN2O2 |
| Molecular Weight | 297.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Methyl 2-amino-3-(5-bromo-1h-indol-3-yl)propanoate (CAS 355017-52-6), molecular formula C12H13BrN2O2 and molecular weight 297.15 g/mol, is a CATO reference standard with documented purity and traceability.
Methyl 2-amino-3-(5-bromo-1h-indol-3-yl)propanoate (C12H13BrN2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H13BrN2O2 |
| Molecular Weight | 297.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Methyl Standards
- 3-(8-Amino-1-bromoimidazo[1,5-a]pyrazin-3-yl)-1-methylcyclobutan-1-ol (CAS 1447607-56-8)
- 1-(3-Amino-4-bromophenyl)-3,3-dimethylpyrrolidine-2,5-dione (CAS 1506034-25-8)
- Methyl 3-(4-amino-6-bromo-1H-indol-2-yl)propanoate (CAS 1527007-68-6)
- Ethyl 2-amino-2-(5-bromo-1H-indol-3-yl)acetate (CAS 1888488-93-4)
- Methyl 2-amino-3-(4-bromo-1H-indol-3-yl)propanoate (CAS 303041-93-2)
- Methyl 2-amino-3-(6-bromo-1H-indol-3-yl)propanoate (CAS 774181-71-4)
- N-(4-Amino-2-chlorophenyl)-5-chloro-2-hydroxybenzamide (CAS 10558-45-9)
- (2E)-2-(5-Amino-1,3,4-thiadiazol-2-yl)-3-(2,4-dichlorophenyl)prop-2-enenitrile (CAS 338775-21-6)
Recommended Standards
- Methyl (R)-2-amino-3-(5-bromo-1H-indol-3-yl)propanoate (CAS 93299-39-9)
- n-(2-(Allylamino)-2-oxoethyl)-4-bromobenzamide (CAS 923198-21-4)
- 8-(Trifluoromethoxy)-2-(trifluoromethyl)quinolin-4-ol (CAS 306935-26-2)
- tert-Butyl (3-bromo-5-cyanophenyl)carbamate (CAS 2092002-01-0)
- Methyl 3-Hydroxybenzofuran-2-carboxylate (CAS 5117-55-5)
- 2-Methyl-5-(3-methyl-1H-pyrazol-5-yl)aniline (CAS 1273550-49-4)
- [4-(2-Hydroxyethyl)-1-piperazinyl](2-piperidinyl)-methanone hydrochloride (CAS 1246172-56-4)
- (S)-3,3'-Bis([1,1':3',1''-terphenyl]-5'-yl)-[1,1'-binaphthalene]-2,2'-diol (CAS 1496637-10-5)
- Ethyl 4-(2-amino-2-oxoethoxy)benzoate (CAS 681444-28-0)
- 2-((5-Bromopyridin-3-yl)methyl)isoindoline-1,3-dione (CAS 219660-71-6)
- 4-(Pyridin-2-ylmethyl)thiomorpholine 1,1-dioxide (CAS 477864-24-7)
- N-(2-Azabicyclo[2.2.1]heptan-6-yl)-5-bromothiazole-2-carboxamide (CAS 524017-40-1)
- 2-amino-3-methoxypropanenitrile hydrochloride (CAS 1432678-73-3)
- Semaglutide Impurity 187 (CAS CATO-C4X-2226187)
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