(2E)-4-(4-Iodophenyl)-4-oxobut-2-enoic acid CAS 35504-88-2
| CAS No. | 35504-88-2 |
| Molecular Formula | C10H7IO3 |
| Molecular Weight | 302.07 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), (2E)-4-(4-Iodophenyl)-4-oxobut-2-enoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies (2E)-4-(4-Iodophenyl)-4-oxobut-2-enoic acid (CAS 35504-88-2), a certified reference material (molecular formula C10H7IO3, MW 302.07 g/mol) for analytical method development and quality control.
The molecular framework of (2E)-4-(4-Iodophenyl)-4-oxobut-2-enoic acid (C10H7IO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, iodine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H7IO3 |
| Molecular Weight | 302.07 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1967 |
| Halogen Content | I-containing |
Related E Standards
- (4-Iodophenyl)(tetrahydrofuran-2-yl)methanone (CAS 1094416-86-0)
- 3-(4-Iodophenyl)piperazin-2-one (CAS 1869195-99-2)
- 1-(4-Iodophenyl)cyclobutanecarboxylic Acid (CAS 630382-89-7)
- Methyl 1-(4-iodophenyl)cyclopropanecarboxylate (CAS 630384-36-0)
- 1-(4-Iodophenyl)-4-methylpiperazine (CAS 1125409-95-1)
- 1-(4-Iodophenyl)hexan-1-one (CAS 160565-78-6)
- trans-4-(4-Iodophenyl)cyclohexanol (CAS 65531-17-1)
- 1-(4-Iodophenyl)cyclopentanemethanamine (CAS 1895253-52-7)
Recommended Standards
- 8-IOdo-imidazo[1,2-a]pyridine-6-carboxylic acid methyl ester (CAS 1823624-38-9)
- 3-iodo-5-methoxy-4H-chromen-4-one (CAS 904318-61-2)
- 6-IOdo-imidazo[1,2-a]pyridine-8-carboxylic acid methyl ester (CAS 1822851-54-6)
- 3-Iodo-6-methoxy-4H-chromen-4-one (CAS 310411-89-3)
- 2-(Methoxymethoxy)-4-(methylthio)butanenitrile (CAS 476301-91-4)
- Ciproxifan hydrochloride (CAS 1049741-81-2)
- 1-ethyl-2-mercapto-1H-benzimidazole-5-sulfonamide (CAS 795291-33-7)
- (S)-2-amino-N-(2,2-diethoxyethyl)-4-methyl-N-phenethylpentanamide (CAS 1222068-64-5)
- Benzo[b]selenophene (CAS 272-30-0)
- 4-[(thien-3-ylcarbonyl)amino]butanoic acid (CAS 930395-61-2)
- N-neopentylnaphthalen-1-amine (CAS 324034-56-2)
- Dichloro[(R)-(+)-2,2’-bis(diphenylphosphino)-1,1’-binaphthyl]palladium(II) (CAS 115826-95-4)
- 5-Methyl-5,11-dihydro-6H-indolo[3,2-c]quinolin-6-one (CAS 85149-47-9)
- Semaglutide impurity 94 (CAS CATO-C4X-222694)
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