8-Chloro-5-(piperazin-1-ylsulfonyl)isoquinoline dihydrochloride CAS 355115-40-1
| CAS No. | 355115-40-1 |
| Molecular Formula | C13H14ClN3O2S |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
8-Chloro-5-(piperazin-1-ylsulfonyl)isoquinoline dihydrochloride (CAS 355115-40-1), molecular formula C13H14ClN3O2SHCl and molecular weight 348.24 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C13H14ClN3O2SHCl, 8-Chloro-5-(piperazin-1-ylsulfonyl)isoquinoline dihydrochloride contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 348.24 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 8-Chloro-5-(piperazin-1-ylsulfonyl)isoquinoline dihydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H14ClN3O2S 2*HCl |
| Molecular Weight | 348.24 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Chloro Standards
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Recommended Standards
- 4-Methyl-5-[(4-pentylcyclohexyl)methyl]-4H-1,2,4-triazole-3-thiol (CAS 866132-83-4)
- 1-(2-Amino-5-methoxyphenyl)ethan-1-one (CAS 23042-77-5)
- 2-(1-Hydroxy-2,5-dimethylcyclohexyl)acetic acid (CAS 1339088-31-1)
- 8-Chloroisoquinolin-1(2H)-one (CAS 1368031-04-2)
- Amidotrizoic Acid-d6 (CAS 1189668-69-6)
- Methyl 2-(methylamino)-2-(4-(trifluoromethyl)phenyl)acetate (CAS 1218255-69-6)
- (1-methoxycyclopropyl)methanol (CAS 912346-81-7)
- 4-Bromodihydrofuran-3(2H)-one (CAS 204926-50-1)
- 2-Acetylthiazole-4-carboxylic acid (CAS 13139-47-4)
- Neuroendocrine Regulatory Peptide-4 (human, mouse, rat) (H-7266.1000) (CAS 922704-18-5)
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