1-(p-Tolyl)-1H-pyrrole-2-carbonitrile CAS 35524-48-2

Purity 97%+In StockPharmaceutical Standards
CAS No.35524-48-2
Molecular FormulaC12H10N2
Molecular Weight182.22 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-(p-Tolyl)-1H-pyrrole-2-carbonitrile CAS 35524-48-2 chemical structure

Description

CATO supplies 1-(p-Tolyl)-1H-pyrrole-2-carbonitrile (CAS 35524-48-2), a certified reference material (molecular formula C12H10N2, MW 182.22 g/mol) for analytical method development and quality control.

The molecular framework of 1-(p-Tolyl)-1H-pyrrole-2-carbonitrile (C12H10N2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 1-(p-Tolyl)-1H-pyrrole-2-carbonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC12H10N2
Molecular Weight182.22 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1967
Nitrogen Atoms2

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