Isobutyl 6-bromo-2-(4-chlorophenyl)quinoline-4-carboxylate CAS 355421-02-2
| CAS No. | 355421-02-2 |
| Molecular Formula | C20H17BrClNO2 |
| Molecular Weight | 418.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Isobutyl 6-bromo-2-(4-chlorophenyl)quinoline-4-carboxylate.
Isobutyl 6-bromo-2-(4-chlorophenyl)quinoline-4-carboxylate (CAS 355421-02-2) is a high-purity analytical reference standard with the molecular formula C20H17BrClNO2 and a molecular weight of 418.71 g/mol.
Structurally, Isobutyl 6-bromo-2-(4-chlorophenyl)quinoline-4-carboxylate (C20H17BrClNO2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 418.71 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H17BrClNO2 |
| Molecular Weight | 418.71 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 1 |
Related Isobutyl Standards
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Recommended Standards
- (Z)-[(4-Bromophenyl)[2-(4-chlorophenyl)cyclopropyl]methylidene]amino cyclopropanecarboxylate (CAS 338415-60-4)
- Methyl 5-(4-bromophenyl)-1-(3-chloro-2-methylphenyl)-2-methyl-1H-pyrrole-3-carboxylate (CAS 881041-72-1)
- 6-Bromo-2-(3-isobutoxyphenyl)quinoline-4-carbonyl chloride (CAS 1160253-13-3)
- tert-butyl (3S)-4-(5-bromo-6-chloro-pyridine-3-carbonyl)-3-methyl-piperazine-1-carboxylate (CAS 2253768-43-1)
- 4-(1,2,3,4,5,6-Hexahydropentalen-1-yl)-1H-imidazole (CAS 628732-30-9)
- 5-Fluoro-2-(methylsulfinyl)pyrimidine (CAS 1967005-91-9)
- 217-90-3 Pyrazino[2,3-f][1,10]phenanthroline DTXSID80471991 (CAS 217-90-3)
- (R)-2-(3,4-Dimethoxyphenyl)pyrrolidine (CAS 1241683-59-9)
- 5-Imino-5,10-dihydro-5l4-phenothiazine 5-oxide hydrochloride (CAS 2137936-69-5)
- Ethyl 3-amino-3-(5-bromo-2-fluorophenyl)propanoate (CAS 780034-35-7)
- 3-Methyl-5-(1-pyrrolidin-3-yl-1h-[1,2,3]triazol-4-yl)-[1,2,4]oxadiazole (CAS 1708428-05-0)
- 4-(1-Piperidyl)benzoic Acid (CAS 22090-24-0)
- 2-(2-methoxyethyl)-2-methylbut-3-enoic acid (CAS 1596663-95-4)
- Semaglutide Impurity 148 (CAS CATO-C4X-2226148)
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