1-Oxo-1-phenylpropan-2-yl 2-(4-bromophenyl)quinoline-4-carboxylate CAS 355428-43-2

Purity 97%+In StockPharmaceutical Standards
CAS No.355428-43-2
Molecular FormulaC25H18BrNO3
Molecular Weight460.32 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-Oxo-1-phenylpropan-2-yl 2-(4-bromophenyl)quinoline-4-carboxylate CAS 355428-43-2 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 460.32 g/mol gives 1-Oxo-1-phenylpropan-2-yl 2-(4-bromophenyl)quinoline-4-carboxylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

1-Oxo-1-phenylpropan-2-yl 2-(4-bromophenyl)quinoline-4-carboxylate (CAS 355428-43-2), molecular formula C25H18BrNO3 and molecular weight 460.32 g/mol, is a CATO reference standard with documented purity and traceability.

1-Oxo-1-phenylpropan-2-yl 2-(4-bromophenyl)quinoline-4-carboxylate (C25H18BrNO3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC25H18BrNO3
Molecular Weight460.32 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at room temperature, protect from light, keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)17.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentBr-containing
Nitrogen Atoms1

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