Methyl 6-chloro-2-(p-tolyl)quinoline-4-carboxylate CAS 355432-94-9
| CAS No. | 355432-94-9 |
| Molecular Formula | C18H14ClNO2 |
| Molecular Weight | 311.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Methyl 6-chloro-2-(p-tolyl)quinoline-4-carboxylate (CAS 355432-94-9) is a high-purity analytical reference standard with the molecular formula C18H14ClNO2 and a molecular weight of 311.76 g/mol.
Structurally, Methyl 6-chloro-2-(p-tolyl)quinoline-4-carboxylate (C18H14ClNO2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 311.76 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H14ClNO2 |
| Molecular Weight | 311.76 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Methyl Standards
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Recommended Standards
- Methyl 2-(2-(4-chlorophenyl)quinolin-6-yl)acetate (CAS 50971-42-1)
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- tert-Butyl 6'-chloro-2',3'-dihydro-1'H-spiro[cyclopropane-1,4'-quinoline]-1'-carboxylate (CAS 2817635-83-7)
- 8-Chloro-2-(pyridin-4-yl)quinoline-4-carbonyl chloride (CAS 1203058-25-6)
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