4-(tert-Butyl)phenyl 2-(4-bromophenyl)quinoline-4-carboxylate CAS 355433-78-2
| CAS No. | 355433-78-2 |
| Molecular Formula | C26H22BrNO2 |
| Molecular Weight | 460.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-(tert-Butyl)phenyl 2-(4-bromophenyl)quinoline-4-carboxylate (C26H22BrNO2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
4-(tert-Butyl)phenyl 2-(4-bromophenyl)quinoline-4-carboxylate (CAS 355433-78-2), molecular formula C26H22BrNO2 and molecular weight 460.36 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C26H22BrNO2 |
| Molecular Weight | 460.36 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- 2-(4-(2-Nitro-4-(trifluoromethyl)phenoxy)benzoyl)-N-phenylhydrazine-1-carboxamide (CAS 1020252-70-3)
- N-(2-((4-bromophenyl)sulfonyl)ethyl)-2-(phenylsulfonyl)propanamide (CAS 337923-69-0)
- Triphenylbis(2,2,2-trifluoroethoxy)phosphorane (CAS 67696-25-7)
- Glutaraldehyd-bis(2,4-dinitrophenylhydrazone) (CAS 5085-07-4)
- N-(2-Hydroxyethyl)-1-[(6-methoxy-5-methyl-4-pyrimidinyl)methyl]-6-methyl-4-azaindole-3-carboxamide (CAS 1494675-86-3)
- (2E)-2-(Benzenesulfonyl)-3-[6-(4-methylphenyl)imidazo[2,1-b][1,3]thiazol-5-yl]prop-2-enenitrile (CAS 691883-96-2)
- N-(4-Methoxybenzyl)methanesulfonamide (CAS 42060-31-1)
- 2-(3-Phenylpropyl)piperidine (CAS 383128-48-1)
- Tetralin-2,5-diol (CAS 35697-11-1)
- CAS 21231-80-1 (CAS 21231-80-1)
- 3-(4-Bromophenoxy)propan-1-amine (CAS 933717-18-1)
- 3-Bromo-N-(p-tolyl)benzenesulfonamide (CAS 1166183-52-3)
- 4-Chloro-2-(2,4-dichlorobenzyl)-6-methyl-1H-pyrrolo[3,4-c]pyridine-1,3(2H)-dione (CAS 261363-78-4)
- Semaglutide impurity 43 (CAS CATO-C4X-222643)
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