(2,2-Dimethylchroman-8-yl)methanol CAS 355837-47-7
| CAS No. | 355837-47-7 |
| Molecular Formula | C12H16O2 |
| Molecular Weight | 192.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
(2,2-Dimethylchroman-8-yl)methanol (CAS 355837-47-7) is a high-purity analytical reference standard with the molecular formula C12H16O2 and a molecular weight of 192.25 g/mol.
The molecular framework of (2,2-Dimethylchroman-8-yl)methanol (C12H16O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C12H16O2 |
| Molecular Weight | 192.25 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
Related Dimethylchroman Standards
- 2,2-Dimethylchroman-4,6-diamine (CAS 1866485-70-2)
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- 2,2-Dimethylchroman-4-carbaldehyde (CAS 93193-94-3)
- 2,2-Dimethylchroman-8-carbaldehyde (CAS 263903-18-0)
- 1-(2,2-Dimethylchroman-6-yl)ethanone (CAS 32333-31-6)
- 1-(2,2-Dimethylchroman-6-yl)-N-methylmethanamine (CAS 1424857-25-9)
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Recommended Standards
- (2,2-Dimethyl-3,4-dihydro-2H-1-benzopyran-6-yl)methanol (CAS 61370-82-9)
- (2E,4E,6E,8E)-2,4,6,8-Decatetraenoic Acid Ethyl Ester (CAS 6071-63-2)
- (1R,2S)-rel-2-(4-Methoxyphenyl)cyclopentanol (CAS 38805-74-2)
- (2-Methoxy-5,6,7,8-tetrahydronaphthalen-1-yl)methanol (CAS 856198-62-4)
- 2-Chloro-5-ethynyl-3-methylpyridine (CAS 1211580-53-8)
- 4,4'-((4-Bromophenyl)azanediyl)dibenzaldehyde (CAS 167859-41-8)
- Cholesterol Chloroformate (CAS 7144-08-3)
- 3-Hydroxy-1H-pyrazolo[4,3-c]quinoline-6-carboxylic acid (CAS 1235659-45-6)
- Ethyl 5-(2-methylphenyl)-1,3,4-thiadiazole-2-carboxylate (CAS 1986907-98-5)
- 3-[5-(1-methyl-1h-pyrazol-4-yl)-3-(trifluoromethyl)-1h-pyrazol-1-yl]propan-1-amine (CAS 1006319-18-1)
- 1-(2-Chloro-4-fluorophenyl)cyclobutanecarboxylic Acid (CAS 1260900-12-6)
- Etoricoxib Impurity 87 (CAS 26524-93-6)
- Ethyl 2-{[(2-cyano-4,5-dimethoxyphenyl)carbamothioyl]amino}acetate (CAS 478039-60-0)
- Semaglutide Impurity 190 (CAS CATO-C4X-2226190)
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