2-(2-Amino-5-fluorophenyl)acetohydrazide CAS 356068-89-8
| CAS No. | 356068-89-8 |
| Molecular Formula | C8H10FN3O |
| Molecular Weight | 183.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 183.18 g/mol gives 2-(2-Amino-5-fluorophenyl)acetohydrazide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-(2-Amino-5-fluorophenyl)acetohydrazide (CAS 356068-89-8) is a high-purity analytical reference standard with the molecular formula C8H10FN3O and a molecular weight of 183.18 g/mol.
The molecular framework of 2-(2-Amino-5-fluorophenyl)acetohydrazide (C8H10FN3O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-(2-Amino-5-fluorophenyl)acetohydrazide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H10FN3O |
| Molecular Weight | 183.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Amino Standards
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Recommended Standards
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- (S)-2-(Boc-amino)-3-methylbutanal (CAS 79069-51-5)
- Riociguat-13C-d3 (CAS 1304478-43-0)
- 4-Chloro-5-((4-methoxybenzyl)oxy)-2-propylpyridazin-3(2H)-one (CAS 88094-10-4)
- 7-Fluoro-4H-benzo[e][1,2,4]thiadiazine 1,1-dioxide (CAS 37162-45-1)
- D-Tyr1-Tirzepatide (CAS CATO-CPTD788928)
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