2-[4-(4-tert-Butylphenoxy)phenyl]-1,3-dioxoisoindoline-5-carboxylic acid CAS 356087-74-6
| CAS No. | 356087-74-6 |
| Molecular Formula | C25H21NO5 |
| Molecular Weight | 415.44 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-[4-(4-tert-Butylphenoxy)phenyl]-1,3-dioxoisoindoline-5-carboxylic acid.
CATO supplies 2-[4-(4-tert-Butylphenoxy)phenyl]-1,3-dioxoisoindoline-5-carboxylic acid (CAS 356087-74-6), a certified reference material (molecular formula C25H21NO5, MW 415.44 g/mol) for analytical method development and quality control.
The molecular framework of 2-[4-(4-tert-Butylphenoxy)phenyl]-1,3-dioxoisoindoline-5-carboxylic acid (C25H21NO5) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C25H21NO5 |
| Molecular Weight | 415.44 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 1 |
Related tert Standards
- 4-(4-tert-Butylphenoxy)-2-{[(4-methylphenyl)methyl]sulfanyl}-5,6,7,8-tetrahydroquinazoline (CAS 551921-45-0)
- 2-(4-tert-Butylphenoxy)-4,6-dimethyl-3-(4-methylbenzenesulfonyl)pyridine (CAS 478245-33-9)
- 1-{[2-(4-tert-butylphenoxy)-1,3-thiazol-5-yl]methyl}-4-phenylpiperazine (CAS 439097-07-1)
- 5-[3-(4-tert-Butylphenoxy)phenyl]-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)cyclohex-2-en-1-one (CAS 685107-58-8)
- 2-(4-tert-Butylphenoxy)-3-(4-chlorobenzenesulfonyl)-4,6-dimethylpyridine (CAS 478245-25-9)
- 3-(4-tert-Butylphenoxy)-2-(4-chlorophenyl)quinoline-4-carboxylic acid (CAS 400079-75-6)
- 2-(4-tert-Butylphenoxy)-3-methanesulfonyl-4-methyl-6-phenylpyridine (CAS 478245-55-5)
- 4-(4-tert-Butylphenoxy)-2-{[(2-chlorophenyl)methyl]sulfanyl}-5,6,7,8-tetrahydroquinazoline (CAS 339019-37-3)
Recommended Standards
- (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-(2,3-dihydrobenzofuran-5-yl)acetic acid (CAS 2349949-70-6)
- 2-{4-[(2,5-dimethylphenyl)methyl]-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-6-carbonyl}benzoic acid (CAS 861212-95-5)
- (19E)-4,17-difluoro-1,5,8,13,15,22,27-heptaazatetracyclo[20.2.2.1¹⁰,¹⁴.0²,⁷]heptacosa-2,4,6,10,12,14,19-heptaen-9-one (CAS 2227259-30-3)
- 2-Fluoro-N-(3-(3-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl)benzamide (CAS 891124-05-3)
- 68807-90-9 Phenolphthalein diphosphate tetrasodium salt sodium 4,4'-(3-oxo-1,3-dihydroisobenzofuran-1,1-diyl)bis(4,1-phenylene) diphosphate (CAS 68807-90-9)
- 2-(4-Ethoxyphenyl)-2-methyloxirane (CAS 1216240-37-7)
- 2-Azabicyclo[2.2.1]heptan-6-ol (CAS 37723-38-9)
- Para Red (CAS 6410-10-2)
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- Acumapimod, >98% (HPLC) (CAS 836683-15-9)
- 5-Chloro-7-fluoro-1H-indole (CAS 1227499-38-8)
- 3-iodo-6-methyl-1H-pyrrolo[3,2-b]pyridine (CAS 1260385-43-0)
- 2-(Difluoromethoxy)benzylamine (CAS 243863-36-7)
- Endo-Pro36-Tirzepatide (CAS CATO-CPTD788688)
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