3-((1,1-Dioxidobenzo[d]isothiazol-3(2H)-ylidene)amino)propyl 2-chloro-2-phenylacetate CAS 356088-58-9
| CAS No. | 356088-58-9 |
| Molecular Formula | C18H17ClN2O4S |
| Molecular Weight | 392.86 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-((1,1-Dioxidobenzo[d]isothiazol-3(2H)-ylidene)amino)propyl 2-chloro-2-phenylacetate (CAS 356088-58-9), molecular formula C18H17ClN2O4S and molecular weight 392.86 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-((1,1-Dioxidobenzo[d]isothiazol-3(2H)-ylidene)amino)propyl 2-chloro-2-phenylacetate (C18H17ClN2O4S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 3-((1,1-Dioxidobenzo[d]isothiazol-3(2H)-ylidene)amino)propyl 2-chloro-2-phenylacetate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H17ClN2O4S |
| Molecular Weight | 392.86 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Dioxidobenzo Standards
- 3-((1,1-Dioxidobenzo[d]isothiazol-3-yl)amino)propyl 2-bromobutanoate (CAS 591212-97-4)
- (((1,1-Dioxidobenzo[b]thiophen-2-yl)methoxy)carbonyl)-L-phenylalanine (CAS 197245-19-5)
- 4-(5-((1,1-Dioxidobenzo[b]thiophen-3-yl)thio)-1H-tetrazol-1-yl)benzoic acid (CAS 1091555-35-9)
- Methyl 2-((1,1-dioxidobenzo[d]isothiazol-3(2h)-ylidene)amino)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate (CAS 568550-83-4)
- 3-((1,1-Dioxidobenzo[d]isothiazol-3-yl)amino)propyl 2-bromopropanoate (CAS 591213-01-3)
- 4-((1,1-Dioxidobenzo[d]isothiazol-3-yl)amino)-N-phenylbenzenesulfonamide (CAS 350509-83-0)
- (((1,1-Dioxidobenzo[b]thiophen-2-yl)methoxy)carbonyl)-L-methionine (CAS 197245-29-7)
- N'-(1,1-dioxidobenzo[d]isothiazol-3-yl)-N,4-dimethylbenzenesulfonohydrazide (CAS 13255-98-6)
Recommended Standards
- 2-(((2-Chlorophenyl)thio)methyl)-5-(3,4,5-trimethoxyphenyl)-1,3,4-oxadiazole (CAS 869357-04-0)
- 3-Amino-4-chloro-n-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1h-pyrazol-4-yl)benzenesulfonamide (CAS 380431-71-0)
- 1-(Phenylsulfonyl)piperidin-4-one O-(4-chlorobenzoyl) oxime (CAS 477847-24-8)
- 4-(4-(Thiophen-2-yl)pyrimidin-2-yl)phenyl 4-chlorobenzoate (CAS 477862-92-3)
- 2-(Methoxymethyl)-2-methylpiperidine (CAS 1150618-41-9)
- 8-Bromo-2-(tert-butoxycarbonyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid (CAS 2138120-40-6)
- 2-(Methylthio)-4,5-dihydro-1H-imidazole Hydroiodide (CAS 5464-11-9)
- 4-Hydroxy-1-(2,4,6-trimethylbenzenesulfonyl)pyrrolidine-2-carboxylic acid (CAS 1007999-66-7)
- 3-Methyl-4-(phenethyloxy)aniline (CAS 112056-23-2)
- 5-Chloro-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione (CAS 835616-62-1)
- phenylthioacetic acid (CAS 103-04-8)
- Methyl 3,5-dibromo-4-fluorobenzoate (CAS 329-43-1)
- trans-2-[2-(2-Methoxyphenyl)-2-oxoethyl]-cyclohexane-1-carboxylic acid (CAS 735274-73-4)
- a-Bag Cell Peptide (1-8) (CAS 87549-53-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com