2-Methyl-5-(methylsulfonyl)-1,3,4-thiadiazole CAS 35647-46-2
| CAS No. | 35647-46-2 |
| Molecular Formula | C4H6N2O2S2 |
| Molecular Weight | 178.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-Methyl-5-(methylsulfonyl)-1,3,4-thiadiazole (CAS 35647-46-2) is a high-purity analytical reference standard with the molecular formula C4H6N2O2S2 and a molecular weight of 178.23 g/mol.
Based on its molecular formula C4H6N2O2S2, 2-Methyl-5-(methylsulfonyl)-1,3,4-thiadiazole contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 178.23 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 2-Methyl-5-(methylsulfonyl)-1,3,4-thiadiazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C4H6N2O2S2 |
| Molecular Weight | 178.23 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1967 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related Methyl Standards
- 4-(Methylsulfonyl)isothiazol-3-amine (CAS 2794197-49-0)
- 5-(Methylsulfonyl)thiazol-2-amine (CAS 20812-13-9)
- 3-methyl-5-(methylsulfonyl)-1,2,4-thiadiazole (CAS 37864-85-0)
- 1-(Methylsulfonyl)azetidine-3-carboxamide (CAS 1428374-79-1)
- 1-((Methylsulfonyl)methyl)cyclopropane-1-carboxylic acid (CAS 1710293-51-8)
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- (R)-1-(methylsulfonyl)piperidin-3-amine (CAS 1232061-19-6)
- (1-(Methylsulfonyl)pyrrolidin-3-yl)methanamine (CAS 1248952-09-1)
Recommended Standards
- 2-Methyl-4-propoxybenzaldehyde (CAS 883531-90-6)
- 2-Methyl-5-(propan-2-yl)benzoic acid (CAS 3754-72-1)
- 2-methyl-3-(piperazin-1-yl)pyrazine (CAS 93263-83-3)
- 2-methyl-5-(pyrrolidin-3-yloxy)pyridine (CAS 946715-59-9)
- 5-Iodo-3-methylisothiazole-4-carbonitrile (CAS 1423700-18-8)
- trans-tert-Butyl ((1r,3r)-3-hydroxy-2,2,4,4-tetramethylcyclobutyl)carbamate (CAS 1338812-41-1)
- Methyl 2-Furancarboxylate (CAS 611-13-2)
- 2,2-difluorocyclopropanesulfonyl chloride (CAS 1935280-15-1)
- Tadalafil EP Impurity I (CAS 2378614-29-8)
- 2-(2,5-Dimethyl-4-(morpholinomethyl)phenoxy)acetamide (CAS 866150-01-8)
- 2-(Chloromethyl)-5-(difluoromethyl)-3-iodo-6-methylpyridine (CAS 1805535-23-2)
- 2-(3,4-Difluorophenyl)-4-((3-methylbut-3-en-1-yl)oxy)-5-(4-(methylsulfonyl)phenyl)pyridazin-3(2H)-one (CAS 890306-92-0)
- Ethyl 5-fluoroisoxazole-4-carboxylate (CAS 25786-81-6)
- Tirzepatide Impurity 35 (CAS CATO-C4X-324035)
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