2-Ethyl 4-methyl 5-(2-chloroacetamido)-3-methylthiophene-2,4-dicarboxylate CAS 356568-69-9
| CAS No. | 356568-69-9 |
| Molecular Formula | C12H14ClNO5S |
| Molecular Weight | 319.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2-Ethyl 4-methyl 5-(2-chloroacetamido)-3-methylthiophene-2,4-dicarboxylate (CAS 356568-69-9), a certified reference material (molecular formula C12H14ClNO5S, MW 319.76 g/mol) for analytical method development and quality control.
The molecular framework of 2-Ethyl 4-methyl 5-(2-chloroacetamido)-3-methylthiophene-2,4-dicarboxylate (C12H14ClNO5S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Ethyl 4-methyl 5-(2-chloroacetamido)-3-methylthiophene-2,4-dicarboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H14ClNO5S |
| Molecular Weight | 319.76 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Recommended Standards
- 2-Chloro-N-(3-cyano-1-(4-fluorobenzyl)-4,5-dimethyl-1H-pyrrol-2-yl)acetamide (CAS 852400-31-8)
- 4-Chlorophenyl quinoline-8-sulfonate (CAS 5409-91-6)
- 2,4-Thiophenedicarboxylic acid, 5-[(2-chloroacetyl)amino]-3-methyl-, 4-ethyl 2-methyl ester (CAS 300676-14-6)
- 4-Chloroquinolin-8-yl benzenesulfonate (CAS 61430-84-0)
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- rac 4-Bocamino-2-phenyl-butyric acid, 98% (CAS 790227-48-4)
- 3-Bromo-6-(trifluoromethyl)pyridine-2-acetic acid (CAS 1214374-35-2)
- 11-Oxo Androsterone (CAS 1231-82-9)
- tert-Butyl 6-(hydroxymethyl)-1-azaspiro[3.3]heptane-1-carboxylate (CAS 1434142-15-0)
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- 2-(Dimethylamino)-10-methyl-4H-benzo[g]chromen-4-one (CAS 68902-40-9)
- Boc-D-Tyr(2,6-dichloro-Bzl)-OH (CAS 69541-62-4)
- (D-His1)-Exenatide trifluoroacetate salt (CAS 1678417-09-8)
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