Ethyl 3-(2-chlorobenzamido)-5-(3-methoxyphenyl)thiophene-2-carboxylate CAS 356586-87-3
| CAS No. | 356586-87-3 |
| Molecular Formula | C21H18ClNO4S |
| Molecular Weight | 415.89 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ethyl 3-(2-chlorobenzamido)-5-(3-methoxyphenyl)thiophene-2-carboxylate.
Ethyl 3-(2-chlorobenzamido)-5-(3-methoxyphenyl)thiophene-2-carboxylate (CAS 356586-87-3), molecular formula C21H18ClNO4S and molecular weight 415.89 g/mol, is a CATO reference standard with documented purity and traceability.
Ethyl 3-(2-chlorobenzamido)-5-(3-methoxyphenyl)thiophene-2-carboxylate (C21H18ClNO4S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Ethyl 3-(2-chlorobenzamido)-5-(3-methoxyphenyl)thiophene-2-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H18ClNO4S |
| Molecular Weight | 415.89 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Ethyl Standards
- Methyl 4-{[2-(4-chlorobenzamido)-4-(trifluoromethyl)phenyl]amino}butanoate (CAS 339101-69-8)
- 1-(2-Chlorobenzamido)-3-cyanopropan-2-yl 3-(trifluoromethyl)benzoate (CAS 339101-94-9)
- Methyl 2-(4-chlorobenzamido)-5-(diethylcarbamoyl)-4-methylthiophene-3-carboxylate (CAS 335406-04-7)
- 1-(4-(4-Chlorobenzamido)benzyl)-N-phenyl-1H-imidazole-4-carboxamide (CAS 1251709-75-7)
- Ethyl 3-(3-chlorobenzamido)-2-oxo-6-phenyl-2H-pyran-5-carboxylate (CAS 339009-30-2)
- Ethyl 3-(4-chlorobenzamido)-2-oxo-6-phenyl-2H-pyran-5-carboxylate (CAS 338404-92-5)
- Methyl 2-(4-chlorobenzamido)-5-(dipropylcarbamoyl)-4-methylthiophene-3-carboxylate (CAS 335407-21-1)
- Ethyl 2-(3-chlorobenzamido)-3-cyano-4,7-dihydrothieno[2,3-c]pyridine-6(5H)-carboxylate (CAS 864927-18-4)
Recommended Standards
- Ethyl 2-{2-[({[(3-chlorobenzyl)oxy]imino}methyl)amino]-1,3-thiazol-4-yl}benzenecarboxylate (CAS 250713-84-9)
- Ethyl 4-(4-chlorophenyl)-5-formyl-2-methyl-6-(pyrimidin-2-ylsulfanyl)-1,4-dihydropyridine-3-carboxylate (CAS 478261-85-7)
- 4-[(N-benzyl4-chlorobenzenesulfonamido)methyl]benzoic acid (CAS 721416-48-4)
- Milenperone (CAS 59831-64-0)
- (S)-2-Amino-3-(3,5-dioxo-1,2,4-triazolidin-1-yl)propanoic acid (CAS 95657-13-9)
- 4-(1H-pyrazol-1-yl)-1,2,3,4-tetrahydroisoquinoline hydrochloride (CAS 1315368-21-8)
- ethyl 5-methylazepane-2-carboxylate (CAS 2089698-69-9)
- 915922-16-6 (6-Fluoro-2-oxo-2,3-dihydro-1H-indol-3-yl)acetic acid DTXSID60679771 (CAS 915922-16-6)
- 1-(6-Methyl-5-phenylthieno[2,3-d]pyrimidin-4-yl)piperidin-4-amine (CAS 660836-09-9)
- 4,7-Dichloro-3-((3-methoxyphenyl)sulfonyl)quinoline (CAS 1400541-28-7)
- 3-(1-(2,4-Dichlorobenzyl)-1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-one (CAS 860784-64-1)
- 4-tert-Butylsulfonylcalix[4]arene (CAS 204190-49-8)
- 7-Chloro-4-methoxyisoquinoline (CAS 1958101-00-2)
- Semaglutide impurity 210 (CAS CATO-C4X-2226210)
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