3,5-Difluoro-4-iodobenzaldehyde CAS 357166-64-4
| CAS No. | 357166-64-4 |
| Molecular Formula | C7H3F2IO |
| Molecular Weight | 268.00 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 3,5-Difluoro-4-iodobenzaldehyde (CAS 357166-64-4), a certified reference material (molecular formula C7H3F2IO, MW 268.00 g/mol) for analytical method development and quality control.
Owing to a hydroxyl group, an ether linkage, fluorine/iodine substitution, an aromatic ring system, 3,5-Difluoro-4-iodobenzaldehyde is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 268.00 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H3F2IO |
| Molecular Weight | 268.00 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/I-containing |
Related Difluoro Standards
- 2,4-Difluoro-5-iodobenzaldehyde (CAS 1097626-30-6)
- 2,6-Difluoro-4-iodobenzaldehyde (CAS 1160573-10-3)
- 2,6-Difluoro-3-iodobenzaldehyde (CAS 1160573-18-1)
- 3,6-Difluoro-2-iodobenzaldehyde (CAS 1208077-39-7)
- 2,4-Difluoro-3-iodobenzaldehyde (CAS 1806292-43-2)
- 2,3-Difluoro-4-iodobenzaldehyde (CAS 885590-99-8)
- 2,3-Difluoro-6-iodobenzaldehyde (CAS 887586-24-5)
- [7,8-difluoro-3-(methoxymethoxy)-1-naphthyl]boronic acid (CAS 2839189-84-1)
Recommended Standards
- 2-Bromo-1-(difluoromethoxy)-3-nitrobenzene (CAS 1174315-54-8)
- 1-Bromo-3-(difluoromethoxy)-5-nitrobenzene (CAS 1261441-47-7)
- (3-(Pyrazin-2-yl)-5-(trifluoromethyl)phenyl)boronic acid (CAS 2225180-54-9)
- 4-Bromo-1-(difluoromethoxy)-2-nitrobenzene (CAS 1261552-41-3)
- methyl 2-cyano-5-fluoropyridine-4-carboxylate (CAS 1807310-34-4)
- tert-Butyl (S)-2-methyl-4,6-dioxopiperidine-1-carboxylate (CAS 653589-14-1)
- Azido-PEG3-S-PEG4-propargyl (CAS 2055041-24-0)
- Z-Ala-OMe (CAS 28819-05-8)
- (3-Ethynylphenyl)glycine (CAS 1040074-05-2)
- 3-(4-(3,3,3-Trifluoropropyl)piperazin-1-yl)propan-1-amine (CAS 1341136-35-3)
- 4-Chloro-6-(methylamino)pyrimidine (CAS 65766-32-7)
- Benzyl N-(5-chloro-2-fluorophenyl)carbamate (CAS 1876328-40-3)
- 2-Hexylzinc bromide 0.5 M in Tetrahydrofuran (CAS 312693-13-3)
- Fragment-[9-31]-Semaglutide (CAS CATO-C4X-2226181)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com