2-Cyano-3-(4-(naphthalen-1-ylmethoxy)phenyl)acrylamide CAS 357229-21-1

Purity 97%+In StockPharmaceutical Standards
CAS No.357229-21-1
Molecular FormulaC21H16N2O2
Molecular Weight328.36 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Cyano-3-(4-(naphthalen-1-ylmethoxy)phenyl)acrylamide CAS 357229-21-1 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 328.36 g/mol gives 2-Cyano-3-(4-(naphthalen-1-ylmethoxy)phenyl)acrylamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

2-Cyano-3-(4-(naphthalen-1-ylmethoxy)phenyl)acrylamide (CAS 357229-21-1), molecular formula C21H16N2O2 and molecular weight 328.36 g/mol, is a CATO reference standard with documented purity and traceability.

2-Cyano-3-(4-(naphthalen-1-ylmethoxy)phenyl)acrylamide (C21H16N2O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-Cyano-3-(4-(naphthalen-1-ylmethoxy)phenyl)acrylamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC21H16N2O2
Molecular Weight328.36 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)15.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Nitrogen Atoms2

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