Brivaracetam Impurity 25 HCl CAS 357338-46-6
| CAS No. | 357338-46-6 |
| Molecular Formula | C13H26N2O3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Brivaracetam Impurity 25 HCl (CAS 357338-46-6) is a certified pharmaceutical impurity reference standard with the molecular formula C13H26N2O3HCl and a molecular weight of 294.82 g/mol.
The molecular framework of Brivaracetam Impurity 25 HCl (C13H26N2O3HCl) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C13H26N2O3 HCl |
| Molecular Weight | 294.82 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Brivaracetam Standards
- Brivaracetam impurity 112 (CAS 10414-69-4)
- Brivaracetam Impurity 56 (CAS 104652-77-9)
- Brivaracetam Impurity 36 (CAS 10547-88-3)
- Brivaracetam Impurity 64 (CAS 112106-16-8)
- Brivaracetam Impurity 23 (CAS 112459-79-7)
- Brivaracetam impurity 103 (CAS 114148-86-6)
- Brivaracetam-d7 (Mixture of Diastereomers) (CAS 1202896-51-2)
- Brivaracetam impurity 98 (CAS 1262340-22-6)
Recommended Standards
- Ursodeoxycholic Acid impurity 76 (CAS CATO-C4X-142276)
- Lemborexant Impurity 40 (CAS CATO-C4X-304240)
- Relugolix Impurity 189 (CAS CATO-C4X-2429189)
- Boc-p-Bz-Phe-OH (CAS 104504-43-0)
- 1-(3-Cyanophenyl)thiourea (CAS 41835-08-9)
- Hemin (CAS 16009-13-5)
- Potassium trifluoro(2-(methylsulfonyl)phenyl)borate (CAS 850623-65-3)
- N-(2-cyano-5-((cyanomethyl)thio)-4-phenylthiophen-3-yl)-4-fluorobenzamide (CAS 860609-93-4)
- 2-((3,5-Dimethylthiophen-2-yl)amino)benzoic acid (CAS 87895-89-4)
- Peptide 435 (CAS CATO-CPTD788435)
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