2-Bromo-3-nitroaniline CAS 35757-20-1
| CAS No. | 35757-20-1 |
| Molecular Formula | C6H5BrN2O2 |
| Molecular Weight | 217.02 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-Bromo-3-nitroaniline is closely related to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2-Bromo-3-nitroaniline (CAS 35757-20-1), a certified reference material (molecular formula C6H5BrN2O2, MW 217.02 g/mol) for analytical method development and quality control.
The molecular framework of 2-Bromo-3-nitroaniline (C6H5BrN2O2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H5BrN2O2 |
| Molecular Weight | 217.02 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1967 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
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- 6-Bromo-2H-oxazolo[3,2-a]pyrimidin-7(3H)-one (CAS 103022-66-8)
- 2-Bromo-5-nitroaniline (CAS 10403-47-1)
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Recommended Standards
- 2-Bromo-3-nitro-6-methylpyridine (CAS 374633-31-5)
- 2-Bromo-4,5-dihydroxybenzaldehyde (CAS 4815-99-0)
- 2-Bromo-3-methyl-5-nitropyridine (CAS 23132-21-0)
- 2-Bromo-4-methyl-5-nitropyridine (CAS 23056-47-5)
- 6-(Tert-butoxycarbonyl)-2,6-diazaspiro[3.3]Heptane-1-carboxylic acid (CAS 1822511-47-6)
- 2,6-Difluoro-N-((1-hydroxycyclopentyl)methyl)benzenesulfonamide (CAS 1235266-56-4)
- Methyl 3-(2-(tert-butoxy)-2-oxoethoxy)benzoate (CAS 367501-39-1)
- 1-(1-methyl-1H-pyrazol-4-yl)-2-(piperazin-1-yl)ethan-1-one dihydrochloride (CAS 1354951-78-2)
- 8,9-Dihydropyrido[1,2-a]indol-6(7H)-one (CAS 91486-93-0)
- 1,1'-(Hexane-1,6-diyl)bis(1-methylpyrrolidin-1-ium) bromide (CAS 13118-09-7)
- 2-Chloro-N-(4-(dimethylamino)cyclohexyl)-N-isopropylacetamide (CAS 1353952-43-8)
- 3-Bromo-N-(furan-2-ylmethyl)-4-methylaniline (CAS 1176655-96-1)
- Benzyl 4-bromobenzoate (CAS 92152-56-2)
- Semaglutide impurity 257 (CAS CATO-C4X-2226257)
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