4-Methylpyrimidine-2-sulfonyl fluoride CAS 35762-74-4
| CAS No. | 35762-74-4 |
| Molecular Formula | C5H5FN2O2S |
| Molecular Weight | 176.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
4-Methylpyrimidine-2-sulfonyl fluoride (CAS 35762-74-4) is a high-purity analytical reference standard with the molecular formula C5H5FN2O2S and a molecular weight of 176.17 g/mol.
The molecular framework of 4-Methylpyrimidine-2-sulfonyl fluoride (C5H5FN2O2S) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C5H5FN2O2S |
| Molecular Weight | 176.17 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1967 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Methylpyrimidine Standards
- 5-Methylpyrimidine-2-sulfonyl fluoride (CAS 35762-75-5)
- 4-Methylpyrimidine-2-sulfonamide (CAS 35762-77-7)
- 5-Methylpyrimidine-2-sulfonamide (CAS 35762-78-8)
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- Semaglutide Impurity 147 (CAS CATO-C4X-2226147)
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