4-Bromo-2,6-bis(trifluoromethyl)quinoline CAS 35853-48-6
| CAS No. | 35853-48-6 |
| Molecular Formula | C11H4BrF6N |
| Molecular Weight | 344.05 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Bromo-2,6-bis(trifluoromethyl)quinoline (C11H4BrF6N) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
4-Bromo-2,6-bis(trifluoromethyl)quinoline (CAS 35853-48-6), molecular formula C11H4BrF6N and molecular weight 344.05 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-Bromo-2,6-bis(trifluoromethyl)quinoline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H4BrF6N |
| Molecular Weight | 344.05 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1967 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
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- 2,3,11,12-Tetrachloro-9,10-dihydro-9,10-ethanoanthracene (CAS 55089-37-7)
- 3-Chloro-1-((2-chloro-5-fluoropyrimidin-4-yl)oxy)-5-(trifluoromethyl)pyridin-2(1H)-one (CAS 1823183-30-7)
- 1,3-Bis((S)-2,2-dimethyl-1-(o-tolyl)propyl)-4,5-dihydro-1H-imidazol-3-ium iodide (CAS 1237025-59-0)
- 2-Cyano-4-hydroxy-N,N-dimethylbenzamide (CAS 1243371-57-4)
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- Methyl 6-amino-5-chloropyrimidine-4-carboxylate (CAS 1956380-48-5)
- Ethyl 2-bromo-4-cyano-6-(trifluoromethyl)benzoate (CAS 1805937-87-4)
- 4,6-dichloro-1H,2H,3H-pyrrolo[2,3-b]pyridin-2-one (CAS 1190322-13-4)
- 3-Amino-n-(pyridin-4-yl)benzamide (CAS 160647-72-3)
- 4-Aminochromane (CAS 53981-38-7)
- Semaglutide Impurity 150 xTFA (CAS CATO-C4X-2226150)
- C-Peptide（dog） (CAS 39016-05-2)
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