4-((4-Phenylpiperazin-1-yl)methyl)benzoic acid CAS 358678-81-6
| CAS No. | 358678-81-6 |
| Molecular Formula | C18H20N2O2 |
| Molecular Weight | 296.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
4-((4-Phenylpiperazin-1-yl)methyl)benzoic acid (CAS 358678-81-6) is a high-purity analytical reference standard with the molecular formula C18H20N2O2 and a molecular weight of 296.36 g/mol.
Structurally, 4-((4-Phenylpiperazin-1-yl)methyl)benzoic acid (C18H20N2O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 296.36 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C18H20N2O2 |
| Molecular Weight | 296.36 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 2 |
Related Phenylpiperazin Standards
- 2-(4-Phenylpiperazin-1-yl)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-ol (CAS 33017-95-7)
- Methyl 6-(4-phenylpiperazin-1-yl)nicotinate (CAS 132521-73-4)
- Methyl 2-(4-phenylpiperazin-1-yl)nicotinate (CAS 400086-57-9)
- (2-([6-(4-Phenylpiperazin-1-yl)pyrimidin-4-yl]oxy)ethyl)amine (CAS 1204296-34-3)
- Ethyl (3-(4-phenylpiperazin-1-yl)propyl)carbamate (CAS 18328-20-6)
- 2-(4-Phenylpiperazin-1-yl)quinoxaline (CAS 338977-24-5)
- 5-(4-Methyl-2-phenylpiperazin-1-yl)thiophene-2-carboxylic acid (CAS 1477971-35-9)
- 2-(4-Phenylpiperazin-1-yl)thiazole-4-carboxylic acid (CAS 952182-67-1)
Recommended Standards
- 4-((1-Benzylpyrrolidin-3-yl)oxy)benzamide (CAS 28506-17-4)
- 4-(2,6,6-Trimethyl-4-oxo-4,5,6,7-tetrahydro-1H-indol-1-yl)benzamide (CAS 497061-30-0)
- 3-Carboethoxy-3-(3-methylphenyl)propiophenone (CAS 898790-51-7)
- 4-(4-(Tert-butyl)benzoyl)phenyl acetate (CAS 890099-70-4)
- 3-amino-1-methylindolizine-2-carbonitrile (CAS 1284237-37-1)
- N1,N6-Diethylhexane-1,6-diamine (CAS 13093-05-5)
- 1-(4-Amino-1,2,5-oxadiazol-3-yl)-5-(methoxymethyl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 312496-15-4)
- 5-Methyl-2-(methylthio)pyrimidine (CAS 100114-24-7)
- 2-(4-methyl-1,3-thiazol-5-yl)ethane-1-sulfonyl chloride hydrochloride (CAS 1803593-54-5)
- Methyl 2-((4-cyano-1-(p-tolyl)-5,6,7,8-tetrahydroisoquinolin-3-yl)thio)acetate (CAS 861209-23-6)
- tert-Butyl 6-oxo-8-azabicyclo[3.2.1]octane-8-carboxylate (CAS 1638772-07-2)
- 4,4'''-(5-Methyl-1,3-phenylene)di-2,2':6',2''-terpyridine (CAS 258834-70-7)
- 1-(3-Chloro-4-methylphenyl)-N-methylmethanamine (CAS 1343065-92-8)
- Peptide YY (3-36) (human) (CAS 123583-37-9)
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