L-Pyroglu-L-His-L-Trp CAS 35925-21-4
| CAS No. | 35925-21-4 |
| Molecular Formula | C22H24N6O5 |
| Molecular Weight | 452.46 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
L-Pyroglu-L-His-L-Trp (CAS 35925-21-4), molecular formula C22H24N6O5 and molecular weight 452.46 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, L-Pyroglu-L-His-L-Trp (C22H24N6O5) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 14.0, corresponding to approximately 14 ring(s) or double-bond equivalent(s). With a molecular weight of 452.46 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), L-Pyroglu-L-His-L-Trp meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H24N6O5 |
| Molecular Weight | 452.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1967 |
| Nitrogen Atoms | 6 |
Recommended Standards
- Ethyl 2-((2-(2-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)amino)-2-oxoethyl)-1-oxo-1,2-dihydroisoquinolin-5-yl)oxy)propanoate (CAS 868224-64-0)
- MERIMEPODIB, VI-21497, VX-497 (CAS 198821-22-6)
- 3-(4-(((2,4-Diamino-5-methylquinazolin-6-yl)methyl)amino)benzamido)pentanedioic acid (CAS 69827-75-4)
- N-(3-Cyano-5-phenylfuran-2-yl)-2-methoxy-N-(2-methoxybenzoyl)benzamide (CAS 478045-56-6)
- (2R,6R)-2,6-Dibenzyl-2,3,5,6-tetrahydro-1H-imidazo[1,2-a]imidazole (CAS 1802738-00-6)
- 3-(2-((2,4-Dichlorobenzyl)oxy)-2-(2,4-dichlorophenyl)ethyl)-1-(2-(4-fluorophenyl)-2-oxoethyl)-1H-imidazol-3-ium chloride (CAS 53597-28-7)
- 1-[4-methoxy-3-(methoxymethyl)phenyl]ethan-1-one (CAS 851288-49-8)
- 4-Cyclopropyl-3-methylbenzaldehyde (CAS 1518035-03-4)
- 1-((5-Bromopyridin-3-yl)sulfonyl)-4-methylpyrrolidin-2-one (CAS 1275420-54-6)
- 4-Methylquinoline-5-carboxylic acid (CAS 1935554-00-9)
- 1-(3-(tert-Butyl)-4-hydroxyphenyl)propan-2-one (CAS 33839-13-3)
- 1-Methyl-2-phenyl-1,2-dihydroquinoline (CAS 887-94-5)
- 9-Methoxy-3,4-dihydro-2H-benzo[b][1,4]dioxepine-7-carboxylic acid (CAS 1010933-59-1)
- Cyclolinopeptide B (CAS 193139-41-2)
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