2-Amino-N-(2,4-difluorophenyl)acetamide CAS 359821-40-2

Purity 97%+In StockPharmaceutical Standards
CAS No.359821-40-2
Molecular FormulaC8H8F2N2O
Molecular Weight186.16 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Amino-N-(2,4-difluorophenyl)acetamide CAS 359821-40-2 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Amino-N-(2,4-difluorophenyl)acetamide.

2-Amino-N-(2,4-difluorophenyl)acetamide (CAS 359821-40-2) is a high-purity analytical reference standard with the molecular formula C8H8F2N2O and a molecular weight of 186.16 g/mol.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 2-Amino-N-(2,4-difluorophenyl)acetamide is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 186.16 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-Amino-N-(2,4-difluorophenyl)acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC8H8F2N2O
Molecular Weight186.16 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF-containing
Nitrogen Atoms2

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