6-Amino-4-(3-chloro-4-fluoroanilino)-3-cyano-7-ethyloxyquinoline CAS 361162-95-0
| CAS No. | 361162-95-0 |
| Molecular Formula | C18H14ClFN4O |
| Molecular Weight | 356.78 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 6-Amino-4-(3-chloro-4-fluoroanilino)-3-cyano-7-ethyloxyquinoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies 6-Amino-4-(3-chloro-4-fluoroanilino)-3-cyano-7-ethyloxyquinoline (CAS 361162-95-0), a certified reference material (molecular formula C18H14ClFN4O, MW 356.78 g/mol) for analytical method development and quality control.
The molecular framework of 6-Amino-4-(3-chloro-4-fluoroanilino)-3-cyano-7-ethyloxyquinoline (C18H14ClFN4O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H14ClFN4O |
| Molecular Weight | 356.78 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related Amino Standards
- 1-(4-((3-Amino-5-chloropyrazin-2-yl)thio)-3,3-difluoroindolin-1-yl)ethan-1-one (CAS 2169224-36-4)
- 3-Amino-N-(1-(2-chloro-4,6-dimethylphenyl)-5-oxo-4,5-dihydro-1H-pyrazol-3-yl)benzamide (CAS 88372-24-1)
- 7-(((3-Amino-1,2,4-thiadiazol-5-yl)sulfonyl)methyl)-5-chloroquinolin-8-ol (CAS 922505-49-5)
- (5-Amino-2-chloropyridin-3-yl)methanol (CAS 1260832-02-7)
- 2-Amino-6-(tert-butyl)-N-(4-ethylphenyl)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide (CAS 588714-57-2)
- 2-Amino-6-(tert-butyl)-N-(4-methylbenzyl)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide (CAS 725226-99-3)
- 2-Amino-6-(tert-pentyl)-N-(m-tolyl)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide (CAS 669740-04-9)
- 2-Amino-6-(tert-pentyl)-N-(o-tolyl)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide (CAS 667436-31-9)
Recommended Standards
- 1-(4-Chlorobenzyl)-N-(2-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide (CAS 946355-10-8)
- XQJ55R5PPQ 882531-87-5 R-1530 UNII-XQJ55R5PPQ 5-(2-Chlorophenyl)-7-fluoro-1,2-dihydro-8-methoxy-3-methylpyrazolo(3,4-b)(1,4)benzodiazepine Pyrazolo(3,4-b)(1,4)benzodiazepine, 5-(2-chlorophenyl)-7-fluoro-1,2-dihydro-8-methoxy-3-methyl- (CAS 882531-87-5)
- N-Nitroso Midazolam EP Impurity A (CAS 59469-02-2)
- 1-(2-Chloro-6-fluorobenzyl)-2-oxo-N-phenyl-1,2-dihydropyridine-3-carboxamide (CAS 478066-01-2)
- 9-Chlorospiro[benzo[c]fluorene-7,9'-fluorene] (CAS 1800333-59-8)
- 5-Bromooxazole-4-carbonitrile (CAS 1097306-76-7)
- TCS 46b (CAS 302799-86-6)
- 3-(5,7-Dichloro-3-indolyl)-1-propanamine Hydrochloride (CAS 1956335-65-1)
- 2-(tert-Butyl)-3-cyclopropoxy-N,N-dimethylbenzamide (CAS 1243444-02-1)
- 5-Amino-2-ethyl-7-(pyridin-4-yl)-1,7-dihydropyrano[2,3-d]imidazole-6-carbonitrile (CAS 374612-98-3)
- (3-(2-Methoxyphenyl)-1,2,4-oxadiazol-5-yl)methanamine (CAS 1211499-10-3)
- Metoprolol Impurity 43 (CAS CATO-C4X-136743)
- 4-(Aminomethyl)-2,2-dimethylheptan-3-ol (CAS 1500928-47-1)
- 69558-55-0 O3Y80ZF13F Thymopentin Thymopentin [USAN:INN:BAN] L-Tyrosine, N-(N-(N-(N2-L-arginyl-L-lysyl)-L-alpha-aspartyl)-L-valyl)- L-Tyrosine, N-(N-(N-(N(sup 2)-L-arginyl-L-lysyl)-L-alpha-aspartyl)-L-valyl)- Thymopentine [French] Thymopentinum [Latin] Timopentina [Spanish] Thymopoietin 32-36 TP-5 Thymopoietin pentapeptide ORF-15244 Thymopentine Thymopentinum Timopentina ORF 15244 UNII-O3Y80ZF13F (CAS 69558-55-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com