3-Bromo-4-chlorothiophene CAS 36155-88-1
| CAS No. | 36155-88-1 |
| Molecular Formula | C4H2BrClS |
| Molecular Weight | 197.48 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 3-Bromo-4-chlorothiophene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
3-Bromo-4-chlorothiophene (CAS 36155-88-1), molecular formula C4H2BrClS and molecular weight 197.48 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-Bromo-4-chlorothiophene (C4H2BrClS) is characterized by sulfur-containing functionality, chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C4H2BrClS |
| Molecular Weight | 197.48 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1967 |
| Halogen Content | Cl/Br-containing |
| Sulfur Atoms | 1 |
Related Bromo Standards
- 2-Bromo-3-chlorothiophene (CAS 77893-68-6)
- 2-Bromo-4-chlorothiophene (CAS 32431-92-8)
- 2-Bromo-5-chlorothiophene (CAS 2873-18-9)
- 3-Bromo-2-chlorothiophene (CAS 40032-73-3)
- 2-Bromo-2-cyclopropylacetyl chloride (CAS 1010802-72-8)
- 2-bromo-1-(1-chlorocyclopropyl)ethanone (CAS 1215365-72-2)
- 3-Bromo-5-(chloromethyl)-1,2,4-oxadiazole (CAS 121562-12-7)
- 5-Bromo-3-(chloromethyl)-1,2,4-oxadiazole (CAS 155742-36-2)
Recommended Standards
- 2,4-Dichlorobenzyl Chloride-d2 (CAS 1246817-90-2)
- 4-Chloro-1-(difluoromethyl)-3-nitro-1h-pyrazole (CAS 1245773-01-6)
- 3-Chloro-6-hydroxy-4-(trifluoromethyl)pyridine (CAS 109919-31-5)
- 3-Chloro-2,5,6-trifluoro-4-methoxypyridine (CAS 1184172-33-5)
- (4-Bromo-2-fluorophenyl)(thiomorpholino)methanone (CAS 1042786-22-0)
- 3-[(4-Chlorophenoxy)methyl]-4-methoxybenzoic acid (CAS 438221-04-6)
- 2-[5-(4-Methoxybenzoyl)-2-thienyl]-3-phenylacrylonitrile (CAS 338966-79-3)
- 5-Amino-1-isopropyl-3-(methylthio)-1h-pyrazole-4-carbonitrile (CAS 1247043-60-2)
- 2-Fluoro-4-iodobenzamide (CAS 1261647-70-4)
- 5-Chloro-2-(cyclopropylmethoxy)aniline (CAS 1021105-81-6)
- N-(6-Oxo-4-phenyl-1,6-dihydropyrimidin-2-yl)acetamide (CAS 54286-78-1)
- 2-Chloro-4-iodobenzaldehyde (CAS 1260810-79-4)
- 2-Chloro-4,6-difluorobenzoic acid (CAS 1242339-67-8)
- Semaglutide Impurity 165 (CAS CATO-C4X-2226165)
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