3-(4-Benzylpiperazin-1-yl)-6-chloropyridazine CAS 362661-27-6
| CAS No. | 362661-27-6 |
| Molecular Formula | C15H17ClN4 |
| Molecular Weight | 288.78 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 3-(4-Benzylpiperazin-1-yl)-6-chloropyridazine (C15H17ClN4) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
3-(4-Benzylpiperazin-1-yl)-6-chloropyridazine (CAS 362661-27-6), molecular formula C15H17ClN4 and molecular weight 288.78 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-(4-Benzylpiperazin-1-yl)-6-chloropyridazine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H17ClN4 |
| Molecular Weight | 288.78 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Benzylpiperazin Standards
- 4-(4-Benzylpiperazin-1-yl)-2-chloropyrimidine (CAS 205060-94-2)
- 1-(4-Benzylpiperazin-1-yl)-2-chloro-2,2-difluoroethan-1-one (CAS 478258-71-8)
- 4-[(4-benzylpiperazin-1-yl)methyl]-1,3-thiazol-2-amine (CAS 1097046-57-5)
- 3-(4-Benzylpiperazin-1-yl)-1,1,1-trifluoropropan-2-ol (CAS 478050-24-7)
- (4-Benzylpiperazin-1-yl)(piperidin-4-yl)methanone (CAS 188527-10-8)
- 2-(4-Benzylpiperazin-1-yl)thiazole-5-carbaldehyde (CAS 303987-22-6)
- N-(4-Benzylpiperazin-1-yl)-2,2,2-trifluoroacetamide (CAS 1198285-47-0)
- (4-Benzylpiperazin-1-yl)(thiophen-2-yl)methanone (CAS 314263-58-6)
Recommended Standards
- 1-((6-Chloropyridin-3-yl)methyl)-4-(pyridin-2-yl)piperazine (CAS 861211-54-3)
- 4-(4-Benzyl-1-piperazinyl)-6-chloropyrimidine (CAS 188527-14-2)
- 6-Amino-8-chloro-4-(neopentylamino)quinoline-3-carbonitrile (CAS 2064105-70-8)
- 1-[6-(2-Chlorophenyl)pyridazin-3-yl]piperidin-4-amine (CAS 1338681-00-7)
- 2-Bromo-5-(4-isopropylphenyl)-1H-imidazole (CAS 1896192-15-6)
- 1-Bicyclo[2.2.1]heptanemethanol (CAS 2064-02-0)
- 4-(2-Fluorobenzyl)-6,7-dimethoxyisoquinoline (CAS 61190-18-9)
- 4-((1H-1,2,4-Triazol-1-yl)methyl)-2-iodoaniline (CAS 160194-26-3)
- 1-(Furan-2-yl)-2-(2-((2-hydroxyethyl)amino)-1H-benzo[d]imidazol-1-yl)ethan-1-one hydrobromide (CAS 435345-13-4)
- 4-Amino-1-(2,6-difluorobenzyl)pyrrolidin-2-one hydrochloride (CAS 1172854-21-5)
- 2-(3-Bromophenoxy)cyclopentan-1-ol (CAS 1184626-99-0)
- 2-(1-Ethyl-1h-pyrazol-4-yl)propan-1-amine (CAS 1248054-96-7)
- 4-(3-Azidopropoxy)-3-methoxybenzoic acid (CAS 2096986-29-5)
- Semaglutide impurity 275 (CAS CATO-C4X-2226275)
Why CATO?
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