Ethyl 3-(4-chlorophenyl)-5-hydroxy-1,2,4-triazine-6-carboxylate CAS 36286-77-8
| CAS No. | 36286-77-8 |
| Molecular Formula | C12H10ClN3O3 |
| Molecular Weight | 279.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ethyl 3-(4-chlorophenyl)-5-hydroxy-1,2,4-triazine-6-carboxylate.
CATO supplies Ethyl 3-(4-chlorophenyl)-5-hydroxy-1,2,4-triazine-6-carboxylate (CAS 36286-77-8), a certified reference material (molecular formula C12H10ClN3O3, MW 279.68 g/mol) for analytical method development and quality control.
The molecular framework of Ethyl 3-(4-chlorophenyl)-5-hydroxy-1,2,4-triazine-6-carboxylate (C12H10ClN3O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Ethyl 3-(4-chlorophenyl)-5-hydroxy-1,2,4-triazine-6-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H10ClN3O3 |
| Molecular Weight | 279.68 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1967 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Ethyl Standards
- 6-(4-Chlorophenyl)-4H,6H,7H-[1,2,3]triazolo[4,3-c][1,4]oxazine-3-carboxylic acid (CAS 1351772-80-9)
- (2-(4-Chlorophenyl)-2H-tetrazol-5-yl)(3-hydroxyazetidin-1-yl)methanone (CAS 1396792-24-7)
- 2-(5-(2-Chlorophenyl)furan-2-carboxamido)acetic acid (CAS 853330-43-5)
- N-((4-chlorophenyl)carbamoyl)-2-(1H-1,2,4-triazol-1-yl)acetamide (CAS 339278-23-8)
- N-(2-Chlorophenyl)-6-hydroxy-1-methyl-2-oxo-1,2-dihydropyrimidine-4-carboxamide (CAS 338774-82-6)
- N-(3-Chlorophenyl)-6-hydroxy-1-methyl-2-oxo-1,2-dihydropyrimidine-4-carboxamide (CAS 338774-83-7)
- N-(4-Chlorophenyl)-6-hydroxy-1-methyl-2-oxo-1,2-dihydropyrimidine-4-carboxamide (CAS 338774-74-6)
- N4-(4-Chlorophenyl)-5-methyl-1,2-oxazole-3,4-dicarboxamide (CAS 338761-32-3)
Recommended Standards
- 6-(6-Chloropyridin-3-yl)-8-oxo-5,7-diazaspiro[3.4]Oct-5-ene-2-carboxylic acid (CAS 2227206-04-2)
- Ethyl 4-(3-chlorobenzoyl)isoxazole-3-carboxylate (CAS 338761-68-5)
- 4-Chloro-2-(2-methylfuran-3-amido)benzoic acid (CAS 926263-39-0)
- Ethyl 4-(4-chlorobenzoyl)isoxazole-3-carboxylate (CAS 952182-77-3)
- 3-(Phenyl(3,5-xylyl)phosphino)propionic acid (CAS 93872-48-1)
- Diethyl 2-(3,5-dioxo-1,2-diphenylpyrazolidin-4-yl)malonate (CAS 6139-70-4)
- N-(2,2,2-Trichloro-1-(pyrrolidin-1-yl)ethyl)nicotinamide (CAS 105624-75-7)
- 1-Bromo-1H-pyrazol-5-amine (CAS 1823380-61-5)
- Methyl 2-((6-chloropyridin-2-yl)thio)acetate (CAS 1258652-80-0)
- methyl 2-(2-fluoro-4-nitrophenyl)-2-methylpropanoate (CAS 1461713-62-1)
- (4-Morpholin-4-ylmethyl-phenoxy)-acetic acid hydrochloride (CAS 1185294-19-2)
- Cyheptamide (CAS 7199-29-3)
- 1-(4-Fluoro-3-methoxyphenyl)piperazine (CAS 740807-09-4)
- D-[Phe]6-Semaglutide (CAS CATO-CPTD788633)
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