10-Chlorobenzo[g]quinoline CAS 3645-26-9
| CAS No. | 3645-26-9 |
| Molecular Formula | C13H8ClN |
| Molecular Weight | 213.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 10-Chlorobenzo[g]quinoline.
10-Chlorobenzo[g]quinoline (CAS 3645-26-9) is a high-purity analytical reference standard with the molecular formula C13H8ClN and a molecular weight of 213.66 g/mol.
The molecular framework of 10-Chlorobenzo[g]quinoline (C13H8ClN) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H8ClN |
| Molecular Weight | 213.66 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chlorobenzo Standards
- 2-(7-Chlorobenzo[d][1,3]dioxol-5-yl)-N-methylethan-1-amine (CAS 1341303-02-3)
- 4-Chlorobenzo[f]isoquinoline (CAS 32081-28-0)
- 7-Chlorobenzo[h]quinoline (CAS 32863-83-5)
- 2-Chlorobenzo[d]thiazole-4-carboxylic acid (CAS 1260529-68-7)
- 2-Chlorobenzo[d]thiazole-7-carboxylic acid (CAS 1379324-66-9)
- 2-Chlorobenzo[d]thiazole-5-carboxylic acid (CAS 1393576-38-9)
- 3-Chlorobenzo[d]isothiazole-6-carboxylic acid (CAS 1520779-76-3)
- 4-Chlorobenzo[d]thiazole-2-carboxylic acid (CAS 3622-02-4)
Recommended Standards
- 1,4-Dihydro-4-oxo-3-quinolinecarbonyl Chloride (CAS 80761-61-1)
- 1-Chloro-3-isopropyl-4-methyl-2-nitro-benzene (CAS 2331260-00-3)
- 1-(tert-Butyl)-2-chloro-4-nitrobenzene (CAS 52756-38-4)
- 2-((3-Chloro-2-methylphenyl)amino)acetohydrazide (CAS 98950-37-9)
- N-(4-MEthoxyphenyl)-4-methyl-2-pyrrolidin-3-ylpyrimidine-5-carboxamide dihydrochloride (CAS 1442086-31-8)
- 5-Chloro-2,8-dimethylquinolin-4-amine (CAS 948292-79-3)
- Tert-butyl (1-(3,3,3-trifluoropropyl)azetidin-3-yl)carbamate (CAS 2231673-84-8)
- 2-Methyl-2,4-Pentanediol (CAS 107-41-5)
- 1241677-90-6 (R)-2-Amino-3-(4-(trifluoromethoxy)phenyl)propanoic acid MFCD07371978 (CAS 1241677-90-6)
- 1,2-Chrysenedione (CAS 2304-83-8)
- 6-(Isobutylamino)pyridazine-3-carboxylic Acid (CAS 1178687-41-6)
- 4-Cyano-3,5-difluorophenyl 4'-propyl-[1,1'-bi(cyclohexane)]-4-carboxylate (CAS 145804-13-3)
- Ethyl 3-(quinolin-4-yl)acrylate (CAS 69976-10-9)
- Liraglutide Sodium Salt (CAS 204656-20-2（free base）)
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