trans-1,1'-(Cyclohexane-1,4-diyl)bis(N-(2-chlorobenzyl)methanamine) dihydrochloride CAS 366-93-8
| CAS No. | 366-93-8 |
| Molecular Formula | C22H28Cl2N2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
trans-1,1'-(Cyclohexane-1,4-diyl)bis(N-(2-chlorobenzyl)methanamine) dihydrochloride (CAS 366-93-8) is a high-purity analytical reference standard with the molecular formula C22H28Cl2N2HCl and a molecular weight of 427.84 g/mol.
trans-1,1'-(Cyclohexane-1,4-diyl)bis(N-(2-chlorobenzyl)methanamine) dihydrochloride (C22H28Cl2N2HCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), trans-1,1'-(Cyclohexane-1,4-diyl)bis(N-(2-chlorobenzyl)methanamine) dihydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H28Cl2N2 2*HCl |
| Molecular Weight | 427.84 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related trans Standards
- Cyclohexane, 5-isocyanato-1-(isocyanatomethyl)-1,3,3-trimethyl-, homopolymer, 2-hydroxyethyl acrylate-blocked (CAS 103458-56-6)
- Cyclohexane-1,4-dicarbonitrile (CAS 10534-13-1)
- 1-Methyl-cyclohexane-1,4-dicarboxylic acid monomethyl ester (CAS 1056639-33-8)
- Cyclohexane (CAS 110-82-7)
- Cyclohexane-1,1-dicarboxylic acid (CAS 1127-08-8)
- 1,4-Cyclohexane dimethanol vinyl ether (cis-trans isomer mixture) (CAS 114651-37-5)
- 1,3-Cyclohexane dimethanol-d<SUB>4</SUB> (CAS 1173022-09-7)
- [1,1'-bi(cyclohexane)]-2-sulfonyl chloride (CAS 1249335-38-3)
Recommended Standards
- 1-Phenyl-3-((3-((3-(trifluoromethyl)phenoxy)methyl)-1H-1,2,4-triazol-5-yl)methoxy)-1H-1,2,4-triazole (CAS 338395-55-4)
- 2-Chloro-2-methylpropanoyl Chloride (CAS 13222-26-9)
- 5-Ethyl-3-(trifluoromethyl)-1H-pyrazole (CAS 436806-62-1)
- 4-(tert-Butyl)-2-(1-phenylethyl)phenol (CAS 1806-32-2)
- N-(2-Bromo-4-methylphenyl)-2-((5-(4-chlorophenyl)-4-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 332947-82-7)
- 4-Acetamido-2-methylquinoline-6-carboxylic acid (CAS 1248565-76-5)
- N-(4-Chlorobenzyl)-4-methylaniline (CAS 33863-79-5)
- Ubidecarenone impurity 23 (CAS 851366-66-0)
- (R)-1-(5-Ethoxypyrazin-2-yl)ethanamine (CAS 1802151-93-4)
- Semaglutide Impurity 82 (CAS CATO-C4X-222682)
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