4-Chloro-1H-pyrazole-5-carbonitrile CAS 36650-75-6
| CAS No. | 36650-75-6 |
| Molecular Formula | C4H2ClN3 |
| Molecular Weight | 127.53 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Chloro-1H-pyrazole-5-carbonitrile (CAS 36650-75-6), molecular formula C4H2ClN3 and molecular weight 127.53 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrile group, chlorine substitution, 4-Chloro-1H-pyrazole-5-carbonitrile is typically off-white to pale yellow liquid. Its solid-state physicochemical attributes — including a molecular weight of 127.53 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-Chloro-1H-pyrazole-5-carbonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C4H2ClN3 |
| Molecular Weight | 127.53 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1967 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 4-Chloro-1H-imidazole-5-carbonitrile (CAS 1333380-68-9)
- 4-Chloro-1H-pyrazole-3-carbonitrile (CAS 33064-35-6)
- 4-Chloro-3-methylpyridine (CAS 1681-36-3)
- 2-Chloro-3-methylpyridine (CAS 18368-76-8)
- 3-Chloro-5-methylpyridine (CAS 19230-55-8)
- 3-Chloro-2-methylpyridine (CAS 72093-03-9)
- 3-Chloro-4-methylpyridine (CAS 72093-04-0)
- 5-Chloro-2-methylpyridine (CAS 72093-07-3)
Recommended Standards
- 5-Chlorofuran-2-carbonitrile (CAS 57240-59-2)
- 4-Chlorofuran-2-carbonitrile (CAS 1399657-96-5)
- 3-(Trimethylsilyl)prop-2-yn-1-amine (CAS 70052-55-0)
- 2-(Trimethylsilyl)propanenitrile (CAS 18151-58-1)
- (S)-2,2,2-Trifluoro-1-(3-methoxyphenyl)ethanamine hydrochloride (CAS 2222471-40-9)
- (S)-N-Boc-3-aminotetrahydrofuran-2-one (CAS 40856-59-5)
- 4-(4-Carboxy-3-fluorophenyl)-3-methylbenzoic acid (CAS 1261964-10-6)
- 2-Oxo-1,2-dihydropyridine-3,5-dicarboxylic acid (CAS 95797-09-4)
- 4-(4-Bromophenyl)-2-{[(4-methoxyphenyl)methyl]amino}-4-oxobutanoic acid (CAS 1042766-80-2)
- 6-Oxo-1,6-dihydropyrimidine-5-carboxylic acid (CAS 65754-04-3)
- 5-Chloro-1H-pyrazolo[3,4-c]pyridin-3-amine (CAS 245325-32-0)
- Dl-Lysine Acetylsalicylate EP Impurity I (CAS CATO-C4X-221135)
- imidazo[1,5-a]pyridin-5-ylboronic acid (CAS 1309980-27-5)
- Peptide Impurity 40 (CAS CATO-CPTD788840)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com