6-Hydroxynicotinamide CAS 3670-59-5
| CAS No. | 3670-59-5 |
| Molecular Formula | C6H6N2O2 |
| Molecular Weight | 138.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 6-Hydroxynicotinamide (C6H6N2O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
6-Hydroxynicotinamide (CAS 3670-59-5), molecular formula C6H6N2O2 and molecular weight 138.12 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 6-Hydroxynicotinamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H6N2O2 |
| Molecular Weight | 138.12 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 2 |
Related Hydroxynicotinamide Standards
Recommended Standards
- 6-Aminopyridine-2-carboxylic Acid (CAS 23628-31-1)
- 6-Methylpyridazine-3-carboxylic Acid (CAS 64210-60-2)
- 6-Amino Nicotinic Acid (CAS 3167-49-5)
- 6-Oxo-1,6-dihydropyridine-2-carboxamide (CAS 89640-67-5)
- 1-(3-((2-Aminoethyl)(cyclopropyl)amino)pyrrolidin-1-yl)ethanone (CAS 1353986-31-8)
- 338982-24-4 5-(Bromomethyl)-1-methyl-3-(trifluoromethyl)-1H-thieno[2,3-c]pyrazole MFCD01935938 (CAS 338982-24-4)
- N-((1H-benzo[d][1,2,3]triazol-1-yl)methyl)propionamide (CAS 164299-68-7)
- 7-Bromo-4-methyl-2H-chromen-2-one (CAS 90767-19-4)
- (R)-N-(piperidin-3-ylmethyl)acetamide (CAS 1820943-84-7)
- methyl 2,2-dimethyl-3-(trifluoromethanesulfonyloxy)propanoate (CAS 1163707-68-3)
- 6-Methoxy-3-phenylquinolin-2-amine (CAS 855837-36-4)
- Benzyl (R)-(3-hydroxy-1-(methoxy(methyl)amino)-1-oxopropan-2-yl)carbamate (CAS 1092473-80-7)
- Viomellein (CAS 55625-78-0)
- (D-His1)-Exenatide trifluoroacetate salt (CAS 1678417-09-8)
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