5-Chloro-2-ethynylphenol CAS 36739-98-7
| CAS No. | 36739-98-7 |
| Molecular Formula | C8H5ClO |
| Molecular Weight | 152.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 5-Chloro-2-ethynylphenol (CAS 36739-98-7), a certified reference material (molecular formula C8H5ClO, MW 152.58 g/mol) for analytical method development and quality control.
Owing to a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, 5-Chloro-2-ethynylphenol is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 152.58 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-Chloro-2-ethynylphenol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H5ClO |
| Molecular Weight | 152.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1967 |
| Halogen Content | Cl-containing |
Related Chloro Standards
- 3-Chloro-1H-pyrrolo[3,2-c]pyridine (CAS 1000342-65-3)
- 2-(2-Chloro-4-pyridyl)acetonitrile (CAS 1000565-45-6)
- 2-(2-Chloro-3-pyridyl)acetonitrile (CAS 101012-32-2)
- 4-Chloro-2-cyano-6-methylpyridine, 97% (CAS 104711-65-1)
- Methyl 4-chloro-3-hydroxybutanoate (CAS 10488-68-3)
- 5-Chloro-2-ethynylpyridin-3-amine (CAS 1150617-82-5)
- 2-Chloro-1H-pyrrolo[2,3-b]pyridine (CAS 1174936-85-6)
- 4-Chloro-6-azaindole (CAS 1188313-15-6)
Recommended Standards
- 5-Amino-2-chlorobenzonitrile (CAS 35747-58-1)
- 5-Chloro-3-ethynylpyridin-2-amine (CAS 866318-88-9)
- 4-Chlorobenzofuran (CAS 257864-14-5)
- 5-Chloro-4-methylnicotinonitrile (CAS 890092-50-9)
- (R)-2-amino-2-(3,4,5-trimethoxyphenyl)ethan-1-ol (CAS 1213956-61-6)
- 2-Amino-3-(methoxycarbonyl)pyrazine 1-Oxide (CAS 17149-35-8)
- Dichloro(1,10-phenanthroline-κN1,κN10)cobalt (CAS 48165-46-4)
- (2R)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-(2H-1,2,3,4-tetrazol-5-yl)propanoic acid (CAS 1464137-20-9)
- 4-Bromo-3-fluorobenzyl bromide, 97% (CAS 127425-73-4)
- 3,6,7-Trimethylpyrrolo[1,2-a]pyrazine (CAS 95407-80-0)
- tert-Butyl 3-ethylpiperidine-3-carboxylate hydrochloride (CAS 2126161-65-5)
- 1-(4-(3,4-Dimethoxyphenyl)-2,5-dimethylfuran-3-yl)ethanone (CAS 88484-90-6)
- (1-Cyclopropylcyclobutyl)methanamine (CAS 1368128-71-5)
- Insulin Degludec Impurity 5 (CAS CATO-C4X-21575)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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