3-Aminobenzenesulfonyl fluoride CAS 368-50-3
| CAS No. | 368-50-3 |
| Molecular Formula | C6H6FNO2S |
| Molecular Weight | 175.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-Aminobenzenesulfonyl fluoride.
3-Aminobenzenesulfonyl fluoride (CAS 368-50-3) is a high-purity analytical reference standard with the molecular formula C6H6FNO2S and a molecular weight of 175.18 g/mol.
3-Aminobenzenesulfonyl fluoride (C6H6FNO2S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-Aminobenzenesulfonyl fluoride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H6FNO2S |
| Molecular Weight | 175.18 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Aminobenzenesulfonyl Standards
- 4-Aminobenzenesulfonyl Fluoride (CAS 98-62-4)
- 2-Aminobenzenesulfonyl chloride (CAS 109061-25-8)
- 3-Aminobenzenesulfonyl chloride (CAS 4431-74-7)
- 2-(2-Aminobenzenesulfonyl)acetonitrile (CAS 189624-69-9)
- 2-(4-Aminobenzenesulfonyl)acetonitrile (CAS 797036-00-1)
- 2-(4-Aminobenzenesulfonyl)propanenitrile (CAS 1251042-34-8)
- 4-(3-Aminobenzenesulfonyl)piperazin-2-one (CAS 953758-11-7)
- [1-(4-aminobenzenesulfonyl)pyrrolidin-2-yl]methanol (CAS 1306676-63-0)
Recommended Standards
- 3-Amino-8-methyl-4H-chromen-4-one (CAS 61423-75-4)
- 3-Cyano-2-phenylpropanoic acid (CAS 442542-97-4)
- 3-Acetyl-4-methoxybenzonitrile (CAS 682320-24-7)
- 3-Cyano-4-ethylbenzoic acid (CAS 684249-28-3)
- rel-(5R,6S)-5-amino-6-phenylpiperidin-2-one (CAS 61298-37-1)
- (Z)-2-((4-chlorophenyl)thio)-N'-hydroxynicotinimidamide (CAS 886360-64-1)
- 3-((4-Bromo-3,5-bis(difluoromethyl)-1h-pyrazol-1-yl)methyl)-4-methoxybenzaldehyde (CAS 1005632-19-8)
- 2-(morpholin-3-yl)acetamide (CAS 1273577-39-1)
- (2-Nitro-4-(trifluoromethyl)phenyl)methanol (CAS 133605-27-3)
- 6-Fluoro-1H-pyrrolo[3,2-c]pyridin-3-amine (CAS 1190315-02-6)
- 3-Chloro-6-methyl-1-benzothiophene-2-carbonyl chloride (CAS 34576-87-9)
- 2-Methyl-1-(oxazol-2-yl)propan-1-one (CAS 898759-12-1)
- 4,4-Dimethyl-1,2,3,4-tetrahydroisoquinoline-8-carbonitrile hydrochloride (CAS 1203686-30-9)
- Semaglutide Impurity 180 (CAS CATO-C4X-2226180)
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