1-[3,5-Bis(trifluoromethyl)phenyl]ethanol CAS 368-63-8
| CAS No. | 368-63-8 |
| Molecular Formula | C10H8F6O |
| Molecular Weight | 258.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 258.16 g/mol gives 1-[3,5-Bis(trifluoromethyl)phenyl]ethanol distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
1-[3,5-Bis(trifluoromethyl)phenyl]ethanol (CAS 368-63-8), molecular formula C10H8F6O and molecular weight 258.16 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-[3,5-Bis(trifluoromethyl)phenyl]ethanol (C10H8F6O) is characterized by a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H8F6O |
| Molecular Weight | 258.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Bis Standards
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Recommended Standards
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- 1-(2-Nitro-4-(trifluoromethyl)phenyl)-1h-1,2,4-triazole (CAS 314250-25-4)
- 2-(1-(3,5-Dimethylphenyl)vinyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2212005-39-3)
- 1-Hydroxy-2-naphthonitrile (CAS 67176-26-5)
- 4-(4-Nitrophenoxy)benzaldehyde (CAS 50961-54-1)
- (S)-3-Aminoazetidin-2-one (CAS 80582-10-1)
- 2-Chloro-N-cyclohexyl-N-methylacetamide (CAS 2567-56-8)
- N,N-dimethyl-4-(trifluoromethyl)-6-(3-(trifluoromethyl)phenoxy)pyrimidin-2-amine (CAS 338792-54-4)
- 3318AF 4-Methyl-2-piperidin-1-yl-pyrimidine-5-carboxylic acid 924872-01-5 C11H15N3O2 (CAS 924872-01-5)
- 4-(Benzo[d]thiazol-2-yl)-1-(m-tolyl)-1H-1,2,3-triazol-5-amine (CAS 1032227-71-6)
- 2-(furan-2-yl)-3,3-dimethylazetidine (CAS 1874469-08-5)
- n-(1-(3-Nitrophenyl)ethyl)cyclopropanamine (CAS 1038311-20-4)
- (Ser(PO?H?)2?2)-Tau Peptide (260-264) PAb Blocking trifluoroacetate salt (CAS 2022956-57-4)
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