3,5-Bis(trifluoromethyl)ethoxybenzene CAS 368-67-2
| CAS No. | 368-67-2 |
| Molecular Formula | C10H8F6O |
| Molecular Weight | 258.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3,5-Bis(trifluoromethyl)ethoxybenzene.
CATO supplies 3,5-Bis(trifluoromethyl)ethoxybenzene (CAS 368-67-2), a certified reference material (molecular formula C10H8F6O, MW 258.16 g/mol) for analytical method development and quality control.
The molecular framework of 3,5-Bis(trifluoromethyl)ethoxybenzene (C10H8F6O) is characterized by a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 3,5-Bis(trifluoromethyl)ethoxybenzene under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H8F6O |
| Molecular Weight | 258.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Bis Standards
- 2-(trifluoromethyl)-6,7-dihydro-9H-pyrano[4,3-e][1,2,4]triazolo[1,5-a]pyrimidin-9-one (CAS 1000932-55-7)
- 1-[4-(trifluoromethyl)pyrimidin-2-yl]-1h-pyrazole-3-carboxylic acid (CAS 1006492-26-7)
- 1-[5-(trifluoromethyl)pyridin-2-yl]-1h-1,2,3-triazole-4-carboxylic acid (CAS 1211585-92-0)
- 2-(4,6-Bis(trifluoromethyl)pyridin-2-yl)ethan-1-amine (CAS 1393575-14-8)
- 2-(5-(Trifluoromethyl)pyridin-2-yl)-2H-1,2,3-triazole-4-carboxylic acid (CAS 1431728-02-7)
- 6-(6-(Trifluoromethyl)pyridin-2-yl)-1,3,5-triazine-2,4(1H,3H)-dione (CAS 1446507-38-5)
- 1-(6-(Trifluoromethyl)pyrimidin-4-yl)-1H-imidazole-4-carboxylic acid (CAS 1707735-59-8)
- 1-(6-(Trifluoromethyl)pyrimidin-4-yl)-1H-pyrazole-3-carboxylic acid (CAS 1710845-99-0)
Recommended Standards
- 2-Bromo-4,6-diisopropylpyrimidin-5-amine (CAS 2387294-66-6)
- 4,4,5,5-Tetramethyl-2-(2-(2-methylcyclopropyl)phenyl)-1,3,2-dioxaborolane (CAS 2621936-38-5)
- 2-[(1E)-2-(4-Ethylphenyl)ethenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 870717-91-2)
- 4,4,5,5-Tetramethyl-2-(3-methyl-2,3-dihydro-1H-inden-4-yl)-1,3,2-dioxaborolane (CAS 2621933-83-1)
- 2,2,2-Trifluoro-1-(3'-methoxy-[1,1'-biphenyl]-4-yl)ethan-1-one (CAS 1443306-54-4)
- 2-Bromo-1-chloro-4-fluoro-3-iodobenzene (CAS 1935178-59-8)
- 4-(((Cyclopropylmethyl)sulfonyl)methyl)piperidine (CAS 1160245-63-5)
- 1-(4-Nitrobenzyl)imidazole (CAS 18994-90-6)
- Methyl 4-(2-methoxyphenyl)-4-oxobutanoate (CAS 99046-13-6)
- Methyl 2-{2-oxo-9-oxatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,12,14-hexaen-14-yl}acetate (CAS 1820687-28-2)
- Azathioprine Impurity 17 (CAS CATO-C4X-146317)
- Pemafibrate Impurity 51 (CAS CATO-C4X-290351)
- 5-(1-Methyl-1H-pyrazol-5-yl)pyrazolo[1,5-a]pyrimidine-7-carboxylic acid (CAS 1443278-87-2)
- Insulin Degludec Impurity 26 (CAS CATO-C4X-215726)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com