3-Difluoromethylaniline CAS 368-99-0
| CAS No. | 368-99-0 |
| Molecular Formula | C7H7F2N |
| Molecular Weight | 143.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 3-Difluoromethylaniline (CAS 368-99-0), a certified reference material (molecular formula C7H7F2N, MW 143.13 g/mol) for analytical method development and quality control.
Owing to a nitrile group, fluorine substitution, an aromatic ring system, 3-Difluoromethylaniline is typically off-white to pale yellow liquid. Its solid-state physicochemical attributes — including a molecular weight of 143.13 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H7F2N |
| Molecular Weight | 143.13 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- 3,5-Difluoro-N-methylaniline (CAS 470458-51-6)
- 4-(Difluoromethyl)aniline (CAS 49658-26-6)
- 3,5-Difluoro-4-methylaniline (CAS 878285-13-3)
- 4,5-Difluoro-2-methylaniline (CAS 875664-57-6)
- Nonanedioic acid, compd. with 1,6-hexanediamine , polymer with 11-aminoundecanoic acid, azacyclotridecan-2-one and hexahydro-2H-azepin-2-one (CAS 54634-98-9)
- 4-(3-Chlorophenyl)-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 80240-38-6)
- methyl 4-(4-methoxy-3,3-dimethyl-but-1-ynyl)benzoate (CAS 2555022-68-7)
- 2-Hydroxy-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-3-carbonitrile (CAS 2256755-07-2)
- Ethyl cyclopropyl(3-nitropyridin-4-yl)carbamate (CAS 797032-05-4)
- 5-Oxo-1-o-tolyl-pyrrolidine-3-carboxylic acid (CAS 56617-44-8)
- 2-Chloro-3-(1,3-dioxan-2-yl)propiophenone (CAS 898785-82-5)
- 2-(Hydroxymethyl)-6-methylphenol (CAS 22470-99-1)
- 2-Cyclopropylpropan-1-amine hydrochloride (CAS 1209286-56-5)
- (Ser(PO?H?)3??·???)-Tau Peptide (379-408) trifluoroacetate salt (CAS 2022956-60-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com