8-(Benzylamino)-1-(2-chlorobenzyl)-3,7-dimethyl-1H-purine-2,6(3H,7H)-dione CAS 368837-78-9
| CAS No. | 368837-78-9 |
| Molecular Formula | C21H20ClN5O2 |
| Molecular Weight | 409.87 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 409.87 g/mol gives 8-(Benzylamino)-1-(2-chlorobenzyl)-3,7-dimethyl-1H-purine-2,6(3H,7H)-dione distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
8-(Benzylamino)-1-(2-chlorobenzyl)-3,7-dimethyl-1H-purine-2,6(3H,7H)-dione (CAS 368837-78-9) is a high-purity analytical reference standard with the molecular formula C21H20ClN5O2 and a molecular weight of 409.87 g/mol.
The molecular framework of 8-(Benzylamino)-1-(2-chlorobenzyl)-3,7-dimethyl-1H-purine-2,6(3H,7H)-dione (C21H20ClN5O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H20ClN5O2 |
| Molecular Weight | 409.87 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related Benzylamino Standards
- 3-(Benzylamino)-4-((4-(4-methoxyphenyl)thiazol-2-yl)amino)-4-oxobutanoic acid (CAS 2096495-93-9)
- 1-(4-(Benzylamino)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-2-yl)-2-methyl-1H-indole-4-carboxamide (CAS 1542705-92-9)
- 3-(Benzylamino)-1-(4-iodophenyl)pyrrolidine-2,5-dione (CAS 1009417-93-9)
- Methyl 3-((benzylamino)methyl)-1-(4-methoxybenzyl)-1H-indole-6-carboxylate (CAS 950763-37-8)
- 3-((Benzylamino)methyl)-N-hydroxy-1-(4-methoxybenzyl)-1H-indole-6-carboxamide (CAS 950763-16-3)
- 1,4-Bis(benzylamino)anthracene-9,10-dione (CAS 2478-79-7)
- 4-(Benzylamino)-2-((3-chloro-4-hydroxyphenethyl)amino)pyrimidine-5-carboxamide (CAS 919486-40-1)
- 4-(Benzylamino)-2-(benzylsulfanyl)-6-(4-methylphenyl)pyrimidine-5-carbonitrile (CAS 303985-64-0)
Recommended Standards
- 5-Methyl-2-(pyrazin-2-yl)-1,3-thiazol-4-yl 2-chloro-4-methanesulfonylbenzoate (CAS 338409-41-9)
- (2E)-1-{4-[(2-chloro-6-fluorophenyl)methoxy]phenyl}-3-[(2,3-dimethylphenyl)amino]prop-2-en-1-one (CAS 477888-59-8)
- 11-(3-Chlorophenyl)-2,3-dimethoxy-5,11,12,12a-tetrahydropyrazolo[3',4':4,5]pyrido[2,1-a]isoquinolin-8(6H)-one (CAS 860788-93-8)
- (2E)-1-{4-[(2-chloro-6-fluorophenyl)methoxy]phenyl}-3-[(2,5-dimethylphenyl)amino]prop-2-en-1-one (CAS 477888-39-4)
- 4-fluoro-N,N-dimethyl-3-nitrobenzene-1-sulfonamide (CAS 61324-91-2)
- (R)-1-(3-Chloro-4-fluorophenyl)ethan-1-amine hydrochloride (CAS 1257106-65-2)
- 2-Imino-1-(3-morpholinopropyl)-3-tosyl-1H-dipyrido[1,2-a:2',3'-d]pyrimidin-5(2H)-one (CAS 606952-31-2)
- 4-Chloro-6,7-dimethoxy-3-nitroquinoline (CAS 99011-29-7)
- (S)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)acetonitrile (CAS 115531-69-6)
- 2-fluoro-2-methylhexanoic acid (CAS 74106-60-8)
- 2-Ethyl-3-(3-oxomorpholino)benzene-1-sulfonyl chloride (CAS 1182728-12-6)
- 2-{6-[(4-chlorophenyl)sulfanyl]pyridazin-3-yl}-2-phenylacetonitrile (CAS 339026-43-6)
- 2-((5H-[1,2,4]Triazino[5,6-b]indol-3-yl)thio)-N-(4-ethoxyphenyl)acetamide (CAS 337505-68-7)
- [D-Ser6]-Semaglutide (CAS CATO-C4X-2226287)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com