6-(3,4-Dichlorophenyl)-2,3,4,6-tetrahydropyrimido[2,1-a]isoindol-6-ol CAS 36951-85-6
| CAS No. | 36951-85-6 |
| Molecular Formula | C17H14Cl2N2O |
| Molecular Weight | 333.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-(3,4-Dichlorophenyl)-2,3,4,6-tetrahydropyrimido[2,1-a]isoindol-6-ol.
6-(3,4-Dichlorophenyl)-2,3,4,6-tetrahydropyrimido[2,1-a]isoindol-6-ol (CAS 36951-85-6), molecular formula C17H14Cl2N2O and molecular weight 333.21 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 6-(3,4-Dichlorophenyl)-2,3,4,6-tetrahydropyrimido[2,1-a]isoindol-6-ol (C17H14Cl2N2O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 6-(3,4-Dichlorophenyl)-2,3,4,6-tetrahydropyrimido[2,1-a]isoindol-6-ol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H14Cl2N2O |
| Molecular Weight | 333.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1967 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
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- 1,3-Difluoro-2-(4-methyl-2-nitrophenoxy)-5-(trifluoromethyl)benzene (CAS 2244086-55-1)
- 8-Methyl-4-[2-(trifluoromethyl)benzoyl]-1-oxa-4-azaspiro[4.5]decane-3-carboxylic acid (CAS 1326810-94-9)
- 3-(2-(4-Methylpiperazin-1-yl)ethyl)aniline trihydrochloride (CAS 1432681-87-2)
- 1-Oxo-2-oxaspiro[4.5]decan-8-yl 4-methylbenzenesulfonate (CAS 1043908-54-8)
- 2-(3-Isobutyl-1-methyl-1h-1,2,4-triazol-5-yl)thiophen-3-amine (CAS 1342876-84-9)
- Rifampicin Impurity 14 (CAS CATO-C4X-145614)
- Apalutamide Impurity 33 (CAS CATO-C4X-274933)
- N-(2,4-difluorophenyl)-2,2-difluoro-2-(4-fluorophenoxy)acetamide (CAS 338792-48-6)
- 3-Bromo-propionimidicacidethylester (CAS 744137-21-1)
- Dibenzo[c,h]indeno[1,2,3-kl]acridine (CAS 36762-09-1)
- TRAF6 Control Peptide trifluoroacetate salt (CAS 852690-80-3)
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