4-bromo-2,3-dihydroisoquinolin-3-one CAS 36963-50-5
| CAS No. | 36963-50-5 |
| Molecular Formula | C9H14BrNO |
| Molecular Weight | 232.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-bromo-2,3-dihydroisoquinolin-3-one (CAS 36963-50-5), molecular formula C9H14BrNO and molecular weight 232.12 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-bromo-2,3-dihydroisoquinolin-3-one (C9H14BrNO) is characterized by an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-bromo-2,3-dihydroisoquinolin-3-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H14BrNO |
| Molecular Weight | 232.12 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1967 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related bromo Standards
- 3-(4-Bromo-3,5-dimethyl-1h-pyrazol-1-yl)propan-1-amine (CAS 1000802-72-1)
- 3-Bromo-5-cyclohexyl-4,5-dihydroisoxazole (CAS 1120214-99-4)
- 2-bromo-1H-indole-3-carbaldehyde (CAS 119910-45-1)
- 4-Bromo-1-(pentan-3-yl)-1h-pyrazol-5-amine (CAS 1247795-11-4)
- 4-Bromo-1-pentyl-1h-pyrazol-3-amine (CAS 1249355-98-3)
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- 6-bromo-5-methyl-indolin-2-one (CAS 1260851-75-9)
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Recommended Standards
- 4-bromo-1-methyl-2,3-dihydro-1H-indol-2-one (CAS 884855-68-9)
- 4-Nitro-2-(trifluoromethyl)benzo[d]oxazole (CAS 573759-00-9)
- 3-(4-Bromo-1H-pyrazol-1-yl)-N,N-dimethylpropan-1-amine (CAS 847818-53-5)
- 5-(Trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidine-2-carboxylic acid (CAS 473994-55-7)
- (S)-5-(Hydroxymethyl)piperidin-2-one (CAS 1846560-21-1)
- tert-Butyl N-[(2-chloro-5-fluorophenyl)methyl]carbamate (CAS 1881295-87-9)
- 5-(3-(Hydroxymethyl)phenyl)pyridin-2-ol (CAS 1111102-81-8)
- 4-[2-(trifluoromethyl)-1,3-thiazol-4-yl]aniline hydrochloride (CAS 1795510-94-9)
- 2-[1-(tert-Butoxycarbonyl)-4-(3-chlorophenyl)piperidin-4-yl]acetic acid (CAS 644982-77-4)
- 6-Isopropyl-1-methyl-2-oxo-1,2-dihydropyridine-3-carboxylic acid (CAS 1123169-36-7)
- 3,4-Dihydro-1(2H)-naphthalenone azine (CAS 66575-46-0)
- 2-Phenyl-6-[(5-sulfanyl-1,3,4-oxadiazol-2-yl)methoxy]-3(2H)-pyridazinone (CAS 900019-82-1)
- 2,4,5-T-Ester (CAS CATO-CCEM500180)
- Galanin Message Associated Peptide (44-59) amide (CAS 125455-59-6)
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