4-(4-Chlorobenzyl)piperidine hydrochloride CAS 36968-94-2
| CAS No. | 36968-94-2 |
| Molecular Formula | C12H16ClN |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-(4-Chlorobenzyl)piperidine hydrochloride (C12H16ClNHCl) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
4-(4-Chlorobenzyl)piperidine hydrochloride (CAS 36968-94-2) is a high-purity analytical reference standard with the molecular formula C12H16ClNHCl and a molecular weight of 246.18 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-(4-Chlorobenzyl)piperidine hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H16ClN HCl |
| Molecular Weight | 246.18 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1967 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chlorobenzyl Standards
- 1-(4-Chlorobenzyl)-5-methyl-3-nitro-1h-pyrazole (CAS 1001510-38-8)
- 1-(3-Chlorobenzyl)-5-methyl-3-nitro-1h-pyrazole (CAS 1001566-82-0)
- 1-(3-Chlorobenzyl)-1H-pyrazol-4-amine (CAS 1002033-41-1)
- 3-(2-Chlorobenzyl)pyrrolidine (CAS 1003561-98-5)
- 1-(3-Chlorobenzyl)-4-isothiocyanato-1h-pyrazole (CAS 1004193-35-4)
- 1-(3-Chlorobenzyl)-5-methyl-1,2-dihydro-3h-pyrazol-3-imine (CAS 1004643-48-4)
- 1-(4-Chlorobenzyl)-2-oxo-N-(3-phenylpropyl)-1,2-dihydro-1,8-naphthyridine-3-carboxamide (CAS 1005291-55-3)
- 1-(2-Chlorobenzyl)-5-methyl-3,4-dinitro-1h-pyrazole (CAS 1005669-24-8)
Recommended Standards
- 6-(4-Methylpiperazine-1-carbonyl)pyridine-3-carbonitrile (CAS 1270786-16-7)
- 3-(5-Fluoro-1H-indol-3-yl)propan-1-ol (CAS 141071-80-9)
- 1-(3-Cyclopentyl-1-methyl-1h-1,2,4-triazol-5-yl)ethan-1-amine (CAS 1343448-35-0)
- 1-Cycloheptylpyrrolidin-3-amine (CAS 1096307-23-1)
- tert-Butyl ((2-methyl-6-(methylthio)pyridin-3-yl)methyl)carbamate (CAS 1355225-19-2)
- methyl 5-hydrazinylpicolinate (CAS 1338224-14-8)
- 2-[(2-furylmethyl)thio]-5-(trifluoromethyl)pyridine (CAS 650617-39-3)
- 4-Ethyl-2-methyl-4h-thieno[3,2-b]pyrrole-5-carboxylic acid (CAS 1051362-36-7)
- 1-Benzyl-4-((2-bromophenyl)sulfonyl)piperazine hydrochloride (CAS 864759-62-6)
- Semaglutide impurity 204 (CAS CATO-C4X-2226204)
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