4-Dimethylamino-1-Phenyl-8-(Trifluoromethyl)-3H-1,5-Benzodiazepin-2-One CAS 36985-47-4
| CAS No. | 36985-47-4 |
| Molecular Formula | C18H16F3N3O |
| Molecular Weight | 347.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Dimethylamino-1-Phenyl-8-(Trifluoromethyl)-3H-1,5-Benzodiazepin-2-One.
CATO supplies 4-Dimethylamino-1-Phenyl-8-(Trifluoromethyl)-3H-1,5-Benzodiazepin-2-One (CAS 36985-47-4), a certified reference material (molecular formula C18H16F3N3O, MW 347.33 g/mol) for analytical method development and quality control.
The molecular framework of 4-Dimethylamino-1-Phenyl-8-(Trifluoromethyl)-3H-1,5-Benzodiazepin-2-One (C18H16F3N3O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-Dimethylamino-1-Phenyl-8-(Trifluoromethyl)-3H-1,5-Benzodiazepin-2-One under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H16F3N3O |
| Molecular Weight | 347.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1967 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
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Recommended Standards
- 3-Methyl-4-(4-methylphenyl)-1-{[3-(trifluoromethyl)phenyl]methyl}-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 860789-70-4)
- Kinetin riboside (CAS 4338-47-0)
- 3-(Boc-amino)-4-[3-(trifluoromethyl)phenyl]butyric Acid (CAS 939802-49-0)
- N-(m-tolyl)-2-(2-(trifluoromethyl)-1H-benzo[d]imidazol-1-yl)propanamide (CAS 866049-65-2)
- 2-(1H-Imidazole-2-carbonyl)-N-methyl-4-nitrobenzamide (CAS 62366-95-4)
- (5-Morpholinopyridin-3-yl)methanamine (CAS 1211519-07-1)
- 4-((2-Chlorothiazol-5-yl)methoxy)benzonitrile (CAS 339018-30-3)
- 2-(4-Methoxyphenyl)-6-phenylpyrazolo[1,5-a]pyrimidin-7-amine (CAS 667872-22-2)
- 3-Amino-1-(2,2,2-trifluoroethyl)pyrrolidin-2-one (CAS 1250382-97-8)
- Methyl 1-((tert-butoxycarbonyl)amino)-3-(cyanomethyl)cyclobutane-1-carboxylate (CAS 2385471-93-0)
- Ethyl 2-(2-Benzimidazolylamino)-6-oxo-1,6-dihydropyrimidine-5-carboxylate (CAS 195251-35-5)
- 3-((3-Bromothiophen-2-yl)methyl)azetidine (CAS 1511712-43-8)
- 29654-55-5 Benzyl alcohol, 3,5-dihydroxy- 5-(Hydroxymethyl)resorcinol 3-06-00-06326 (Beilstein Handbook Reference) BRN 2326351 3,5-Dihydroxybenzyl alcohol EINECS 249-751-8 (CAS 29654-55-5)
- (Leu31,Pro34)-Peptide YY (human) trifluoroacetate salt (CAS 179986-95-9)
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