4-(6-Methyl-1H-indol-3-yl)thiazol-2-amine CAS 370077-70-6
| CAS No. | 370077-70-6 |
| Molecular Formula | C12H11N3S |
| Molecular Weight | 229.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-(6-Methyl-1H-indol-3-yl)thiazol-2-amine is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-(6-Methyl-1H-indol-3-yl)thiazol-2-amine (CAS 370077-70-6), molecular formula C12H11N3S and molecular weight 229.30 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-(6-Methyl-1H-indol-3-yl)thiazol-2-amine (C12H11N3S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-(6-Methyl-1H-indol-3-yl)thiazol-2-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H11N3S |
| Molecular Weight | 229.30 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Recommended Standards
- 4-(5-Methyl-1H-indol-3-yl)-thiazol-2-ylamine (CAS 50825-17-7)
- 4,6-Dimethyl-2-(1-methylhydrazino)-3-(methylsulfonyl)pyridine (CAS 341967-36-0)
- 4-(5,6-Dimethyl-1H-benzo[d]imidazol-2-yl)thiazole (CAS 91843-61-7)
- 4-Ethoxy-n-ethylbenzenesulfonamide (CAS 477482-95-4)
- Methyl guaiazulene-3-carboxylate (CAS 39665-58-2)
- Ethyl 5-(((tert-butoxycarbonyl)amino)methyl)-1,3,4-oxadiazole-2-carboxylate (CAS 164029-51-0)
- 3,4-Diiodothiophene (CAS 19259-08-6)
- tert-Butyl ((4-fluoro-6-formylpyridin-2-yl)methyl)carbamate (CAS 1393568-86-9)
- 3-Cyclohexaneamidobenzoic acid (CAS 180991-55-3)
- Olanzapine Impurity 32 (CAS CATO-C4X-117832)
- 3-(4-Ethylcyclohexyl)azetidin-3-ol (CAS 1496755-53-3)
- Benzyl 2-(2,2,2-trifluoroacetyl)hydrazinecarboxylate (CAS 866478-74-2)
- 5-Chloro-3,4-dihydro-1,8-naphthyridin-2(8H)-one (CAS 1237535-79-3)
- Semaglutide impurity 276 (CAS CATO-C4X-2226276)
Why CATO?
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