1-[3-(bromomethyl)phenyl]-2,2,2-trifluoroethan-1-one CAS 370104-05-5

Purity 97%+In StockPharmaceutical Standards
CAS No.370104-05-5
Molecular FormulaC9H6BrF3O
Molecular Weight267.04 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-[3-(bromomethyl)phenyl]-2,2,2-trifluoroethan-1-one CAS 370104-05-5 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 267.04 g/mol gives 1-[3-(bromomethyl)phenyl]-2,2,2-trifluoroethan-1-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

1-[3-(bromomethyl)phenyl]-2,2,2-trifluoroethan-1-one (CAS 370104-05-5) is a high-purity analytical reference standard with the molecular formula C9H6BrF3O and a molecular weight of 267.04 g/mol.

The molecular framework of 1-[3-(bromomethyl)phenyl]-2,2,2-trifluoroethan-1-one (C9H6BrF3O) is characterized by a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC9H6BrF3O
Molecular Weight267.04 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at room temperature, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF/Br-containing

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