4-Methyl-5-((naphthalen-1-yloxy)methyl)-4H-1,2,4-triazole-3-thiol CAS 370563-52-3

Purity 97%+In StockPharmaceutical Standards
CAS No.370563-52-3
Molecular FormulaC14H13N3OS
Molecular Weight271.34 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-Methyl-5-((naphthalen-1-yloxy)methyl)-4H-1,2,4-triazole-3-thiol CAS 370563-52-3 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 271.34 g/mol gives 4-Methyl-5-((naphthalen-1-yloxy)methyl)-4H-1,2,4-triazole-3-thiol distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

4-Methyl-5-((naphthalen-1-yloxy)methyl)-4H-1,2,4-triazole-3-thiol (CAS 370563-52-3), molecular formula C14H13N3OS and molecular weight 271.34 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 4-Methyl-5-((naphthalen-1-yloxy)methyl)-4H-1,2,4-triazole-3-thiol (C14H13N3OS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC14H13N3OS
Molecular Weight271.34 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Nitrogen Atoms3
Sulfur Atoms1

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