4-(Chloromethyl)-N-methyl-1,3-thiazol-2-amine CAS 37060-74-5
| CAS No. | 37060-74-5 |
| Molecular Formula | C5H7ClN2S |
| Molecular Weight | 162.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 162.64 g/mol gives 4-(Chloromethyl)-N-methyl-1,3-thiazol-2-amine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
4-(Chloromethyl)-N-methyl-1,3-thiazol-2-amine (CAS 37060-74-5), molecular formula C5H7ClN2S and molecular weight 162.64 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-(Chloromethyl)-N-methyl-1,3-thiazol-2-amine (C5H7ClN2S) is characterized by a nitrile group, sulfur-containing functionality, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H7ClN2S |
| Molecular Weight | 162.64 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1967 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chloromethyl Standards
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- 5-(chloromethyl)-4,6-dimethylpyrimidine (CAS 1823959-87-0)
Recommended Standards
- 4-(2-chloroethyl)-1,3-thiazol-2-amine (CAS 79386-89-3)
- 2-(5-Chlorothiophen-2-yl)ethan-1-ol (CAS 553653-39-7)
- 5-Chloro-3-(propan-2-yl)-1,2,4-thiadiazole (CAS 51302-12-6)
- [(5-Chlorothiophen-2-yl)methyl]hydrazine (CAS 887592-42-9)
- Pent-4-yn-1-yl benzoate (CAS 100330-28-7)
- Tetraphenylphosphonium hexafluoroantimonate (CAS 124329-50-6)
- 5-Amino-1-(4-bromobenzyl)-1H-1,2,3-triazole-4-carbonitrile (CAS 850374-96-8)
- L-Ornithine-2,3,3,4,4,5,5-d7 hydrochloride (CAS 2483831-57-6)
- (3S,4AR,6aR,6bS,8aR,12aR,14aR,14bR)-4,4,6a,6b,8a,11,11,14b-octamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicen-3-yl palmitate (CAS 5973-06-8)
- 2-Amino-3-(3-(methoxycarbonyl)phenyl)propanoic acid hydrochloride (CAS 2376143-22-3)
- 4-Bromo-2-chloro-5-methylanisole (CAS 179897-95-1)
- 1-(4-Methoxyphenyl)propane-2-thiol (CAS 36427-87-9)
- 4-(3-Pyrazin-2-yl-propyl)-piperidine-4-carboxylic aciddimethylamide dihydrochloride (CAS 1361116-23-5)
- Tirzepatide Impurity 44 (CAS CATO-C4X-324044)
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