2-(3-Fluorophenyl)-1-(4-fluorophenyl)ethan-1-one CAS 370874-66-1
| CAS No. | 370874-66-1 |
| Molecular Formula | C14H10F2O |
| Molecular Weight | 232.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2-(3-Fluorophenyl)-1-(4-fluorophenyl)ethan-1-one (CAS 370874-66-1), molecular formula C14H10F2O and molecular weight 232.23 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-(3-Fluorophenyl)-1-(4-fluorophenyl)ethan-1-one (C14H10F2O) is characterized by a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 2-(3-Fluorophenyl)-1-(4-fluorophenyl)ethan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H10F2O |
| Molecular Weight | 232.23 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
Related Fluorophenyl Standards
- 1-(2-Fluorophenyl)-2-(3-fluorophenyl)ethanone (CAS 1183418-91-8)
- 1-(2-Fluorophenyl)-2-(4-fluorophenyl)ethanone (CAS 1184754-66-2)
- 2-((2-Fluorophenyl)sulfonyl)acetohydrazide (CAS 1325307-28-5)
- 2-((4-Fluorophenyl)sulfonyl)-N-hydroxyacetimidamide (CAS 175203-76-6)
- 1-(3-Fluorophenyl)-2-(4-fluorophenyl)ethanone (CAS 476472-53-4)
- 2,2-bis(4-fluorophenyl)acetaldehyde (CAS 2054-14-0)
- 3-[(2-fluorophenyl)sulfonyl]propanoic acid (CAS 874594-06-6)
- 3-[(4-Fluorophenyl)sulfonyl]propanoic acid (CAS 682760-24-3)
Recommended Standards
- 2-(3,4-Difluorophenyl)-1-phenylethan-1-one (CAS 845781-26-2)
- 2-(5-Hydroxy-6-methoxynaphthalen-1-yl)acetic acid (CAS 24039-88-1)
- 2-(2-Acetyl-6-methyl-1-benzofuran-3-yl)acetic acid (CAS 864466-10-4)
- 2-((4-Fluorobenzyl)sulfonyl)acetic acid (CAS 222639-41-0)
- 4-(4-Chlorophenyl)-6-methylpyrimidin-2-amine (CAS 19927-54-9)
- 3-Amino-1-(4-phenylphenyl)urea (CAS 124351-95-7)
- N-(Cyclohexylmethyl)piperidin-4-amine (CAS 867009-08-3)
- DPPI 1c Hydrochloride (CAS 866396-70-5)
- Tert-butyl (4-((4-cyanobenzyl)amino)cyclohexyl)carbamate (CAS 1286264-38-7)
- 5-(Difluoromethoxy)picolinic acid (CAS 1174323-34-2)
- (S)-4-Methyl-2-(5-(trifluoromethyl)pyridin-2-yl)-4,5-dihydrooxazole (CAS 1803416-27-4)
- (2-Butyl-3-benzofuranyl)[4-(2-hydroxyethoxy)-3,5-diiodophenyl]methanone (CAS 135048-44-1)
- 3-Chloro-N,N-diethylbenzamide (CAS 15952-65-5)
- Acetyl decapeptide-3 (CAS 935288-50-9)
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