2-(4-(4-Chlorophenyl)piperazin-1-yl)-5-(propan-2-ylidene)thiazol-4(5H)-one CAS 371208-15-0
| CAS No. | 371208-15-0 |
| Molecular Formula | C16H18ClN3OS |
| Molecular Weight | 335.85 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2-(4-(4-Chlorophenyl)piperazin-1-yl)-5-(propan-2-ylidene)thiazol-4(5H)-one (CAS 371208-15-0) is a high-purity analytical reference standard with the molecular formula C16H18ClN3OS and a molecular weight of 335.85 g/mol.
Based on its molecular formula C16H18ClN3OS, 2-(4-(4-Chlorophenyl)piperazin-1-yl)-5-(propan-2-ylidene)thiazol-4(5H)-one contains a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 335.85 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 2-(4-(4-Chlorophenyl)piperazin-1-yl)-5-(propan-2-ylidene)thiazol-4(5H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H18ClN3OS |
| Molecular Weight | 335.85 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Chlorophenyl Standards
- N-[4-(4-Chlorophenyl)-1,3-thiazol-2-yl]-2-(piperidin-1-yl)acetamide (CAS 101436-55-9)
- 1-(4-((4-(4-Chlorophenyl)thiazol-2-yl)methyl)piperazin-1-yl)ethan-1-one (CAS 1172016-47-5)
- 2-(4-Chlorophenyl)-N-[2-(4-methylbenzenesulfinyl)ethyl]acetamide (CAS 477710-73-9)
- 4-(6-{[(4-chlorophenyl)sulfanyl]methyl}-2-methylpyrimidin-4-yl)morpholine (CAS 477866-84-5)
- N-(2-((4-chlorophenyl)sulfinyl)ethyl)-2-(m-tolyl)acetamide (CAS 955976-86-0)
- 3-{[(4-chlorophenyl)methyl]sulfanyl}-5-[(E)-2-(dimethylamino)ethenyl]-1,2-thiazole-4-carbonitrile (CAS 338778-57-7)
- 1-(4-Chlorophenyl)heptan-2-yl 2-(oxazol-4-yl)acetate (CAS 89006-89-3)
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Recommended Standards
- (1-Methylcycloprop-2-en-1-yl)benzene (CAS 65051-83-4)
- N-(4-Chloro-3-((3-methylbut-2-en-1-yl)oxy)phenyl)-2-methylfuran-3-carbothioamide (CAS 178870-32-1)
- 3-(4-Chlorobenzyl)-1-tosylazetidine (CAS 1375472-94-8)
- 5-Chloro-2-ethoxy-N-(3-ethoxypropyl)-4-methylbenzenesulfonamide (CAS 898645-71-1)
- N-Hexyl 3-bromo-5-trifluoromethylbenzenesulfonamide (CAS 951884-63-2)
- 5-Amino-3-fluoropyridin-2-ol (CAS 1373233-01-2)
- Ethyl 2-ethoxy-4-methylthiazole-5-carboxylate (CAS 156498-54-3)
- 4-Bromo-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine (CAS 1083181-71-8)
- Ethyl (E)-3-(3,4-dichlorophenyl)acrylate (CAS 82475-77-2)
- 4-chlorocarbendazole (CAS 55214-28-3)
- 4-(1-Methylsiletan-1-yl)benzaldehyde (CAS 873292-81-0)
- 5-(Acetyloxy)-1,3-oxathiolane-2-methanol Benzoate (CAS 146726-76-3)
- 1-(4-(5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl)piperazin-1-yl)ethan-1-one (CAS 1201644-39-4)
- Semaglutide impurity 100 (CAS CATO-C4X-2226100)
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