5-(4-Bromophenyl)-4-(4-ethoxybenzoyl)-3-hydroxy-1-(5-methyl-1,3,4-thiadiazol-2-yl)-1H-pyrrol-2(5H)-one CAS 371220-53-0
| CAS No. | 371220-53-0 |
| Molecular Formula | C22H18BrN3O4S |
| Molecular Weight | 500.37 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
5-(4-Bromophenyl)-4-(4-ethoxybenzoyl)-3-hydroxy-1-(5-methyl-1,3,4-thiadiazol-2-yl)-1H-pyrrol-2(5H)-one (CAS 371220-53-0) is a high-purity analytical reference standard with the molecular formula C22H18BrN3O4S and a molecular weight of 500.37 g/mol.
5-(4-Bromophenyl)-4-(4-ethoxybenzoyl)-3-hydroxy-1-(5-methyl-1,3,4-thiadiazol-2-yl)-1H-pyrrol-2(5H)-one (C22H18BrN3O4S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures 5-(4-Bromophenyl)-4-(4-ethoxybenzoyl)-3-hydroxy-1-(5-methyl-1,3,4-thiadiazol-2-yl)-1H-pyrrol-2(5H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H18BrN3O4S |
| Molecular Weight | 500.37 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Bromophenyl Standards
- 2-(4-Bromophenyl)-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-6-phenyl-1,5,6,7-tetrahydro-4H-indol-4-one (CAS 1023798-69-7)
- 3-((4-Bromophenyl)sulfonyl)-N-(m-tolyl)thieno[2,3-e][1,2,3]triazolo[1,5-a]pyrimidin-5-amine (CAS 892749-88-1)
- N-(4-bromophenyl)-2-((3-cyano-4,6-diphenylpyridin-2-yl)thio)acetamide (CAS 299164-53-7)
- N-(3-bromophenyl)-2-((3-methyl-4-oxo-7-(p-tolyl)-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl)thio)acetamide (CAS 1111265-56-5)
- N-(4-Bromophenyl)-2-{[3-methyl-7-(4-methylphenyl)-4-oxo-3H,4H-thieno[3,2-d]pyrimidin-2-yl]sulfanyl}acetamide (CAS 1111318-01-4)
- N-(3-bromophenyl)-2-((3-ethyl-4-oxo-7-phenyl-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl)thio)acetamide (CAS 1223781-89-2)
- N-(4-bromophenyl)-2-((3-ethyl-4-oxo-7-phenyl-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl)thio)acetamide (CAS 1223924-08-0)
- 2-[(4-Bromophenyl)sulfanyl]-N-[3-fluoro-4-(4-phenylpiperazin-1-yl)phenyl]acetamide (CAS 866136-81-4)
Recommended Standards
- Ethyl 6-methyl-7-oxo-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-tosyl-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxylate (CAS 1628864-26-5)
- Fosfomycin Impurity 28 (CAS CATO-C4X-131628)
- Apixaban Impurity 51 (CAS CATO-C4X-108851)
- N-(4-chloro-3-nitrophenyl)-2-((5-(4-chlorophenyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 443739-90-0)
- Penicillanic Acid Potassium (CAS 4027-63-8)
- (1H-Pyrrolo[3,2-c]pyridin-2-yl)methanamine (CAS 438571-18-7)
- 4-Aminohex-5-ynoic acid (CAS 57659-38-8)
- 3-Formamidopropanoic acid (CAS 14565-43-6)
- 1-(4-(Tert-butyl)benzyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (CAS 1562304-58-8)
- Ethyl 3-bromo-5,6,7,8-tetrahydroimidazo[1,2-a]pyridine-2-carboxylate (CAS 2138569-78-3)
- 4-Methoxymethylcyclohexylmethanol (CAS 98955-27-2)
- 1-(1-(4-Chlorophenyl)-3,5-dimethyl-1h-pyrazol-4-yl)-N-methylmethanamine (CAS 1292691-62-3)
- 1-((1R,2S)-2-Methylcyclopentyl)-1H-pyrrole (CAS 752206-05-6)
- Semaglutide impurity 268 (CAS CATO-C4X-2226268)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com